Osteoarthritis, Told, Part I Flashcards

(50 cards)

1
Q

what is the msot common arthropathy

A

OA

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2
Q

OA involves what part of joint

A

cartilage

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3
Q

primary OA

A

aging or idiopathic

genetic: nodal OA

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4
Q

secondary OA

A

dut to disorders that damage joint surfaces

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5
Q

2 principle mech of OA

A

damage to normal articular cartilage by physical forces

defective cartilage failures under normal joint loading

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6
Q

what occurs with there is physical damage to cartilage in OA

A

chondrocytes react with degenerative enzymes

inadequate repair response

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7
Q

what are the defects of fundamental defective cartilage OA

A
type II collagen gene defect (Ochronosis)
Ochronotic cartilage (pigmented and defective)
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8
Q

what are the pathologic characteristics of OA joint

A
loss of cartilage
sclerosis
remodeling bone
osteophyte spurs
cystic changes
mild reactive synovitis
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9
Q

systemic Factors for OA

A
age
obesity
genetics
gender W>M
menopause? maybe
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10
Q

local factors for OA

A
muscle strength
joint proprioception
repetitive use
configuration of joint
trauma
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11
Q

common joints in OA

A
cervical spine
lumbar spine
1st CMC
PIP
DIP
Hip
Knee
1st MTP
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12
Q

uncommon joints of OA

A
shoulder
throacic spine
elbow
wrist
MCP
ankle
subtalar
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13
Q

What are signs of nodal OA

A

heberdens nodes
bouchards nodes
1st CMC joint: base of thumb

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14
Q

where are heberdens nodes

A

DIP

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15
Q

where are bouchards nodes

A

PIP

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16
Q

most common location OA

A

knee

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17
Q

Sx OA

A
insidious onset
pain with movement
limitation motion, dec function
minimal stiffness after rest
referred pain
acute flares suggest another Dx
systemic Sx
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18
Q

why is OA painful

A

its the synovitis and ligament stretching
periosteal irritation, muscle spasms
intraosseous HTN

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19
Q

signs of OA

A
bony changes in joint shape
crepitus
malalignment/instability
limited ROM
joint line tenderness
cool effusions
spasm or atrophy of adjacent muscles
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20
Q

what are the non specific Dx tests for OA

A

ESR, RF

synovial fluid

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21
Q

What do you see on XR for OA

A

cartilage loss/joint space narrowing
subchondral sclerosis
osteophytes at joint margins
subchondral cysts

22
Q

what are subsets of OA

A
generalized
nodal
spondylosis
erosive
inflammatory
DISH
chondromalacia patellae
23
Q

DISH

A

diffuse idiopathic skeletal hyperostosis

24
Q

what occurs in spondylolysis

A

the pars interarticularis breaks

25
what occurs in spondylolisthesis
pars interarticularis breaks and spine slips
26
what is genu varus
wide knees
27
what part of knee sees msot wear
medial compartment
28
what are syndesmophytes
osteophytes that connect bones together
29
what happends with spondylosis in cervical spine
dysphagea
30
what happens with spondlyosis of lumbar spin
radiculopathy
31
what causes DISH
``` excessive osteophytosis of spine 3-4 segments preservation of disc spaces ligametnous calcifications M>F unilateral ```
32
DISH is assoc with
DM
33
up flowing osteophytes
DISH
34
is DISH inflammatory
no
35
where are the osteoblasts that cause DISH
in entheses
36
what side is most often affected by DISH
R side | L side if have dextro cardia or situs inversus
37
environmental factors for DISH
fluoride synthetic retinoids obesity IGF-1
38
calcifications of posterior longitudinal ligament
DISH
39
best place to look for DISH
thoracic spine, flowing anterior osteophytes
40
upward pointing lumabr osteophytes
DISH
41
ligamentous calcification at enthesis
=whisker calcifications | DISH
42
what is chondromalacia of patella
whiskering and abnormal rubbing/growth patella
43
chondromalacia patella more common
wide hip women because more stress on knees
44
Tx goals for OA
pain control improve fucntion enhance health related quality of life avoid Rx
45
how to manage OA
``` education weight loss analgesics NSAIDs PT OT srugery ```
46
What are SMOADs
structure modifying anti-osteoarthritis dugs
47
types of SMOADs
matrix metalloprotesase inhibitors MMPI | residronate, doxy, glucosamine, chondroitin
48
if inflammatory OA does not respond to cochicine
Ca pyrophosphate joint crystals
49
Rx for inflammatory OA
colchicine
50
pain relieved with rest morning stiffness, goes away with movement little articular inflammation
OA