Vasculitis part I

Question 1

What causes vasculitis

Answer 1

IC and actiation of C’

Question 2

what do you see in vasculitis vessel

Answer 2

damage to walls
leukocytoclastic changes
necrosis and thrombosis

Question 3

clinical Sx of vasculitis is determined how

Answer 3

vessel size

Question 4

what are the constitutional Sx in vasculitis

Answer 4

fever, weight loss, malaise

Question 5

what are the large vessel vasculitis clinical manifestations

Answer 5

limb claudication
asymmetric BP
absence of pulses
bruits
aortic dilation

Question 6

clinical manifestations of medium vessel vasculitis

Answer 6

ulcers
arthritis
livedo reticularis
digital gangrene
Mononeuritis multiplex!!
microaneurysms

Question 7

clinical manifestations of small vessel vasculitis

Answer 7

purpura
urticaria
glomerulonephritis
alveolar hemorrhage
arthritis
splinter hemorrhages
uveitus
episcleritis
scleritis

Question 8

behcets

Answer 8

vessel vasculitis of any size

Question 9

What are the large vessel vasculitis

Answer 9

takayasu arteritis

giant cell arteritis

Question 10

what are the medium vessel vasculitis

Answer 10

polyarteritis nodosa

kawasaki disease

Question 11

what are the small vessel vasculitis

Answer 11

ANA assoc

IC associated

Question 12

What are the ANCA related small vessel vasculitis

Answer 12

microscopic polyangiitis
granulomatosis with polyangiitis(wegener)
eosinophilic granulomatosis with polyangiitis (churg strauss)

Question 13

What are the IC related small vessel vasculitis

Answer 13

Ant GBM
cryoglobulinemic vasculitis
IgA HSP
hypocomplemetemic urticarial vasculitis

Question 14

what are the variable vessel vasculitis

Answer 14

behcets

cogans IgG4 related

Question 15

what are the single organ vasculitis

Answer 15

cutaneous vasculitis

primary CNS vasculitis “string of beads”

Question 16

most common presentation of vasculitis syndrome

Answer 16

palpable purpura

Question 17

what causes inflammatroy palpable purpura

Answer 17

leukocytoclastic vasculitis

Question 18

what is used for Tx remission vasculitis

Answer 18

glycocorticoids and cyclophosphamides

Question 19

maintenance of vasculitis

Answer 19

AZA or MTX or mycophenolate

Question 20

what is temporal arteritis

Answer 20

granulomatous giant cell arteritis

Question 21

takayasu arteritis race

Answer 21

asian

Question 22

BP different in R arm compared to L

Answer 22

large arter vasculitis

Question 23

2 phases of takayasu arteritis

Answer 23

early inflammatory and late occlusive

Question 24

bruit heard where in takayasu

Answer 24

subclavian or aorta

Question 25

what is pulseless disease and Tx

Answer 25

takayasu arteritis | Tx steroids

Question 26

jaw claudication or pain with chewing

Answer 26

temporal arteritis

Question 27

stenosis wehre with temporal arteritis

Answer 27

subclavian stenosis or aneurysm

Question 28

Sed rate is extremely high

Answer 28

temporal arteritis

Question 29

fever of unknown origin

Answer 29

temporal arteritis

Question 30

What can termporal arteritis look like

Answer 30

polymyalgia theumatica

Question 31

main signs temporal arteritis or giant cell

Answer 31

``` >50 y.o Feve unkown origin paraneoplastic jaw claudication proximal pain and stiffness elevated ESR inc alk phos ```

Question 32

``` left wrist drop and right foot drop fever arthralgias HTN hematuria testicular tenderness hep B + med size vesslaneurysms ```

Answer 32

polyarteritis nodosum

Question 33

signs polyarteritis nodosum

Answer 33

][livedo reticularis | foot drop or polyneuropathy

Question 34

Sx polyarteritis nodosum

Answer 34

``` HTN fever weight loss abdominal pain lungs spared testicular pain or tenderness myalgias ```

Question 35

labs for polyarteritis nodosa

Answer 35

azotemia, anemia Hep B virus Bx skin nerve muscle or testicles angiogram renal, mesenteric hepatic artery

Question 36

med vessel aneurysms

Answer 36

polyarteritis nodosa

Question 37

child with fever for 5 days erythema and edema palms soles cervical adenopathy

Answer 37

Kawasaki syndrome

Question 38

concerned about what in kawasaki disease

Answer 38

coronary artery aneurysm

Question 39

kawasaki disease criteria

Answer 39

needs fever >5 days 4/5 of the following: - conjunctivitis - rash: erythematous, maculopapular, mobiliform -erythema palms and soles -adenopathy, cervical - mucous membrane dry red strawberry tongue

Question 40

lab to order in kawasaki disease

Answer 40

echo to make sure heart is okay

Question 41

SLE patient with wheals that don't go away followed by echymosis C' levels low

Answer 41

urticarial vasculitis

Question 42

what is the Anti C1q vasculitis

Answer 42

hypocomplemetemic urticarial vasculitis

Question 43

what produce urticaria ain urticarial vasculitis

Answer 43

C3a and C5a

Question 44

what cause urticarial vasculitis

Answer 44

CT diseases | hep B or C

Question 45

what causes hypocomplementemic form urticarial vasculitis

Answer 45

SLE with Ab to Cq1 and vascular endothelial cells

Question 46

``` 18 y.o with fever palpable skin lesions arthralgias hematuria abdominal pain GI bleeding Ig involved ```

Answer 46

IgA

Question 47

Sx with HSP

Answer 47

purpura arthritis GI abdominal pain with bleeding

Question 48

what is the single organ IgA disease

Answer 48

beurgers

Question 49

typical UA finding in HSP

Answer 49

RBC cast in urine

Question 50

sat on cold bleacher and caused necrotizing vasculitis

Answer 50

mixed cryoglobulinemia

Question 51

what to eval patient for with mixed cryoglobulinemia

Answer 51

hep C