Other AP

Question 1

Dx of: lymphocytic bronchiolitis, mild interstitial lymphocytic inflammation, and poorly-formed granulomas

Answer 1

Hypersensitivity pneumonitis (Extrinsic allergic alveolitis)

Question 2

3 findings in Hypersensitivity pneumonitis

Answer 2

lymphocytic bronchiolitis
mild interstitial lymphocytic inflammation
poorly-formed granulomas

Question 2

1p, 19q

Answer 2

Co-deletion in oligodendroglioma

Question 3

Most common genetic aberration in meningioma

Answer 3

Ch 22

Question 4

Isochromosome 17q

Answer 4

Most common genetic abnormality in medulloblastoma

Question 5

Genetic alteration in medulloblastoma with poor prognosis

Answer 5

Myc amplification

Question 6

Intraventricular brain tumors

Answer 6

SEGA
Ependymoma
Subependymoma
Choroid plexus tumors
Pineal tumors
Colloid cyst

Question 7

Cystic tumor with mural nodule

Answer 7

Pilocytic astrocytoma
PXA
Ganglion cell tumor
Hemangioblastoma
Craniopharyngioma

Question 8

Most common H&N location for lobular capillary hemangioma

Answer 8

Anterior nasal septum (Kisselbach’s triangle)

Question 9

Causative agent of rhinoscleroma

Answer 9

Klebsiella rhinoscleromatis

Organisms seen in Mikulicz cells (clear histiocytes)

Question 10

Causative agent of rhinosporidiosis

Answer 10

Rhinosporidium seeberi

Question 11

Triad of histo findings in Wegeners

Answer 11

Geographic necrosis
Granulomatous inflamm
Vasculitis

Question 12

Histology findings in cylindrical cell papilloma (oncocytic schneiderian papilloma)

Answer 12

2 cell layers
Cilia
Intraepithelial mucin cysts
Goblet cells
Neutrophils

Question 13

Most common sarcoma of H&N

Answer 13

Rhabdomyosarcoma

Question 14

Nasopharyngeal carcinoma assd with…

Answer 14

EBV

Question 15

Looks like colon carcinoma in nose

Answer 15

High-grade sinonasal adenocarcinoma

May have mucinous or signet ring cell types

Question 16

Assd with occupational exposures to wood dust and leather processing

Answer 16

High-grade (intestinal type) sinonasal adenocarcinoma

Question 17

Ddx with malignant granular cell tumor

Answer 17

Paraganglioma

Alveolar soft part sarcoma

Question 18

Prognosis of spindle cell carcinoma of larynx

Answer 18

Generally poor, but do not tend to invade deeply due to polyploid growth pattern

Question 19

Chronic otitis media with glandular inclusions

Answer 19

It exists

Question 20

Itchy periaural papules that bleed

Answer 20

Angiolymphoid hyperplasia with eosinophilia
Histo similar to Kimura dz
Assd lymphadenopathy and peripheral eosinophilia

Question 21

Benign ear tumor that may look like carcinoid

Answer 21

Middle ear adenoma

Question 23

Papillary neoplasm of endolymphatic sac origin (Heffner tumor)

Answer 23

Assd with VHL

Arises in temporal bone

Question 24

Most common cause of allergic fungal sinusitis

Answer 24

dematiaceous fungi

Question 25

Location of inverted papilloma

Answer 25

lateral nasal wall

Question 26

Respiratory epithelial adenomatoid hamartoma

Answer 26

(REAH) ddx of inverted papilloma periglandular hyalinization thin respiratory epithelium

Question 27

Stains positive in glomangiopericytoma

Answer 27

SMA, Factor XIIIA

Question 28

Staining in olfactory neuroblastoma

Answer 28

s100 in sustentacular pattern

Question 29

Staining in sinonasal undifferentiated carcinoma

Answer 29

cytokeratin only

Question 30

ddx of sinonasal undifferentiated carcinoma

Answer 30

``` sinonasal neuroendocrine carcinoma lymphoepithelial carcinoma Ewing/PNET Melanoma Rhabdomyosarcoma ```

Question 31

Rhomboid crystals on EM

Answer 31

alveolar soft part sarcoma

Question 32

"corncob" on EM

Answer 32

melanosome (melanoma, clear cell sarcoma)