Other tumor stuff + tumor buzzwords Flashcards Preview

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Flashcards in Other tumor stuff + tumor buzzwords Deck (15):
1

what is the most common benign CNS primary?

Meningioma

2

what is the most common malignant CNS Primary

Glioblastoma

3

what is the most common CNS tumor overall?

Metastatitc Disease

50% from lung

4

Signs and Symptoms of CNS tumors?

Non Specific FIndings from Increased ICP (bradycardia, HTN, N/V, confusion, CN VI Palsy)

Localized and specific -- motor weakness, CN palsy, Speech loss, vision loss,

Excitatory -- new onset sz

Behaviora l-- Frontal lobe syndromes

Endocrine --

5

Diagnositics for CNS tumors

MRI +/- Spine imaging

Histopathology

Molecular diagnsostics

6

Buzzwords:

Pseudopallisading?

Glioblastoma

7

Buzzwords

Fried egg with chicken wire

Oligodendroglioma

8

Buzzwords

Rosettes and Pseudorossettes

Ependymoma

9

Homer Write pseudorossettes

Medulloblastoma

10

Cystic appearance with "Mural nodule in the cerebellum

Pilocytic Astrocytoma

Hemangioblastoma

11

Biphasic architecture + Rosenthal Fibers

Pilocytic Astrocytoma

12

"whorls" and "psammoma Bodies"

what is the tumor?
what is the associated molecular pathology?
where is this molecular change seen?

Meningioma

Merlin/Schawnnomin (Loss of 22q12.2) tumor suppressor

Also seen with NF 2 (Schwannomas)

13

Tumor which can cause secondary polycythemia ?

• Hemangioblastoma --

14

Antoni A (w/verocay bodies) and Antoni B

8th cranial nerve schwannaoma

15

Plexiform Neurofibroma

Neurofribromatosis Type 1