Flashcards in Other tumor stuff + tumor buzzwords Deck (15):
what is the most common benign CNS primary?
what is the most common malignant CNS Primary
what is the most common CNS tumor overall?
50% from lung
Signs and Symptoms of CNS tumors?
Non Specific FIndings from Increased ICP (bradycardia, HTN, N/V, confusion, CN VI Palsy)
Localized and specific -- motor weakness, CN palsy, Speech loss, vision loss,
Excitatory -- new onset sz
Behaviora l-- Frontal lobe syndromes
Diagnositics for CNS tumors
MRI +/- Spine imaging
Fried egg with chicken wire
Rosettes and Pseudorossettes
Homer Write pseudorossettes
Cystic appearance with "Mural nodule in the cerebellum
Biphasic architecture + Rosenthal Fibers
"whorls" and "psammoma Bodies"
what is the tumor?
what is the associated molecular pathology?
where is this molecular change seen?
Merlin/Schawnnomin (Loss of 22q12.2) tumor suppressor
Also seen with NF 2 (Schwannomas)
Tumor which can cause secondary polycythemia ?
• Hemangioblastoma --
Antoni A (w/verocay bodies) and Antoni B
8th cranial nerve schwannaoma