Oxygenation Flashcards
(94 cards)
Alterations in respiratory function:
hypoventilation
hyperventilation
hypoxia
Hypoventilation:
Alveolar ventilation is inadequate to meet the oxygen demand of the body or eliminate sufficient carbon dioxide
Atelectasis is
a collapse of the alveoli, prevents normal exchange of oxygen and carbon dioxide
Hypoxia is
inadequate tissue oxygenation at the CELLULAR level.
Results from a deficiency in oxygen delivery or oxygen use at the cellular level
life threatening
Hypoxemia is
suboptimal normal partial pressure of oxygen.
Untreated hypoxemia will result in hypoxia.
Hypoxemia is common cause of hypoxia however hypoxia can exist without hypoxemia
Causes of Hypoxemia
Poor alveolar ventilation due to decreased tidal volume or respiratory rate
Decreased diffusion of oxygen from alveoli to pulmonary capillaries as a result of THICKENING of the alveolar-capillary membrane ventilation/perfusion mismatch
Shunting- occurs when venous blood travels from the right to left side of heart without passing by inflated alveoli resulting in MIXING of venous and arterial blood
Ventilation/perfusion mismatch
Causes of Hypoxia:
Anemic hypoxia
Ischemic stagnant hypoxia
Histotoxic hypoxia/dysoxia
Anemic hypoxia:
decreased ability to transport oxygen and can be result of low hemoglobin levels (anemia, hypovolemic shock) or reduced function of hemoglobin (carbon monoxide poisoning)
Ischemic/stagnant hypoxia:
occurs when there is decreased delivery of oxygen to tissue cells as a result of insufficient blood flow and which may be the result of systemic conditions (cardiac failure) or local disruption to circulation (tissue edema or local arterial damage).
Histotoxic hypoxia:
occurs when tissues are unable to properly utilize oxygen despite adequate oxygen supply and which occurs as a result of cellular poisons (cyanide), abnormal tissue oxygen requirements, or poor oxygen diffusion across cell membrane (tissue edema)
Hypoxemia ranges:
pO2 of less than 60 mmHG or an oxygen saturation of less than 90% leaving oxygen saturations in the range of 90-95%
Respiratory failure is defined as a
pO2 less than 50 mmHg and a pCO2 greater than 50 mmHG
Ventilation:
process of moving gases into and out of the lungs
Atelectasis:
collapse of the alveoli that prevents normal exchange of oxygen and carbon dioxide
External respiration:
exchange of O2 and CO2 between alveoli and blood
Gas transport:
blood transports O2 and CO2 to body cells
Internal respiration
exchange of O2 and CO2 between blood and cells
Blood and tissue oxygenation is through the process of ___________ (3)
Ventilation
Perfusion
Diffusion
Accumulation of carbonic acid in the body leads to
respiratory acid-base disorder termed respiratory acidosis
Majority of CARBON DIOXIDE molecules are transported in the blood as
BICARBONATE HCO2
Factors affecting respiration could stem from
integrity of the airway system (ventilation)
functioning cardiovascular system (perfusion)
functioning alveoli (diffusion)
functioning medulla & chemoreceptors
Physiologic factors Gas-exchange:
decrease oxygen-carrying capacity
hypovolemia
decrease inspired oxygen concentration
increased metabolic rate
Physiologic factors affecting gas-exchange:
Lung elasticity/compliance (ability to stretch and recoil)
Airway obstruction
musculature condition
trauma
neuromuscular disease
central nervous system
influences of chronic disease
Alteration in cardiac function that could affect oxygenation:
cardiac arrhythmias
congestive heart failure
valvular dysfunction
cardiac ischemia