P1: Long Exam 1 Flashcards

(100 cards)

1
Q

The normal straw color of urine is largely due to the presence of

A

urochrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Emptying the bladder or urine voiding is otherwise known as

A

micturition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which set of parts involved in urine formation is correctly sequenced?

A. glomerulus, proximal convoluted tubule, loop of Henle, renal pelvis, collecting ducts, ureter, urinary bladder, urethra
B. glomerulus, proximal convoluted tubule, renal pelvis, loop of Henle, collecting ducts, ureter, urinary bladder, urethra
C. glomerulus, proximal convoluted tubule, loop of Henle, collecting ducts, renal pelvis, ureter, urinary bladder, urethra
D. glomerulus, proximal convoluted tubule, collecting ducts, loop of Henle, renal pyramid, ureter, urinary bladder, urethra

A

C. glomerulus, proximal convoluted tubule, loop of Henle, collecting ducts, renal pelvis, ureter, urinary bladder, urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The procedure of wet urinalysis starts with the

A

sample identification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Amino acid disorders are characterized by the passage of urine with

A

characteristic odors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

characteristic odors

A

hematuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

One of the following is characterized by a turbid urine due to leakage of lymph:
A. pyuria
C. bacteruria
B. chyluria
D. cylindruria

A

B. chyluria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Brick dust refers to which of the following crystals?

A

amorphous urates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Gross examination of urine samples involve all of the following except

A. assessment of odor
C. pH and specific gravity testing
B. reporting of urine color
D. measurement of urine volume

A

C. pH and specific gravity testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The clearing of turbidity due to the addition of a dilute acid confirms the presence of

A

amorphous phosphates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The presence of casts in the urine is called

A

cylindruria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The purpose of collecting timed urine samples is for obtaining
A. more yield, thus, increased sample volume
B. higher concentration of a particular substance tested
C. more urinary sediments such as cells, crystals and casts
D. ensure high degree of accuracy and precision of chemical tests

A

B. higher concentration of a particular substance tested

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Any transient increase in urinary volume is termed

A

diuresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The most commonly encountered abnormal color of urine is

A

red-brown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The TS (Total Solids) meter or refractometer is used to measure

A

specific gravity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The presence of many mucus threads in the urine indicates

A

renal inflammatory episode

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

PKU or phenylketonuria is a disease characterized by the voiding of a

A

mousy-smelling urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

A reagent strip is sometimes referred to as the

A

dipstick

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Regarded as the routine or basic urinalysis is the
A. wet urinalysis
C. reagent strip urinalysis
B. special cytologic urinalysis
D. chemical urinalysis

A

A. wet urinalysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Macroscopic examination of urine includes the following except
A. appearance
C. chemical testing using multistix
B. specific gravity determination
D. sediment examination

A

C. chemical testing using multistix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

In the event that only one urine specimen is obtained, which correct sequence should be followed in wet urinalysis?

  1. bacteriologic examination 3. examination for crystals and casts
  2. check for contamination 4. glucose testing

A. 1-2-3-4
B. 2-1-4-3
C. 1-2-4-3
D. 2-1-3-4

A

B. 2-1-4-3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

The patient’s degree of hydration and urine concentration can be estimated by examining

A

urine color

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Small cloudy patches in normal urine due to the presence of mucus is called

A

nubecula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Which pigment causes the production of yellow foam ?

A

bilirubin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Presence of intact red blood cells is called
hematuria
26
Homogentisic acid forms brown-black urine upon long standing -- a condition known as
alkaptonuria
27
Which of these urinary constituents can be cleared through acidification? A. amorphous urates B. amorphous phosphates C. pus cells D. bacteria
B. amorphous phosphates
28
The dye Oil Red O is used to demonstrate the presence of
lipiduria
29
Excretion by an adult of more than 500 mL. of urine with a specific gravity of 1.018 at night is known as
nocturia
30
Which of the following statements is not true? A. High volumes of urine result in a low specific gravity. B. The aromatic odor of freshly voided urine is of undetermined source. C. Cloudy urine is not common and not necessarily pathologic. D. Aside from urochrome, there are other pigments that give normal urine a yellow color.
D. Aside from urochrome, there are other pigments that give normal urine a yellow color.
31
A urine sample with a specific gravity of 1.010 is described as
isosthenuric
32
Which parameter cannot be measured using reagent strip technology?
osmolality
33
Sound wave frequency and falling drop method are performed to assess the urine
specific gravity
34
The state of hydration of the patient can be assessed by all of the following except A. urine osmolality B. urine volume and color C. urine specific gravity D. urine pH
D. urine pH
35
The presence of high amounts of indican will give a urine sample a
blue-green color
36
The average adult on a normal diet produces a 24-hour urine with a pH of about
6.0
37
At night, during the mild respiratory acidosis of sleep, a more acidic urine is formed. The acidity is largely due to the buildup of
carbon dioxide
38
A diet high in meat and cranberries will
lower urinary pH
39
The ill effects of salicylic acid poisoning would be aggravated by which of the following: A. diet rich in meat B. intake of sodium bicarbonate C. diet high in citrus fruits D. prohibition of acid phosphate ingestion
A. diet rich in meat
40
In the tubular cells, the passing filtrate acquire hydrogen ions in exchange for
sodium ions
41
Which pair of dipstick and its number of chemical parameters is incorrect? A. Multistix 10 SG - 10 B. Uristix -2 C. Diastix – 2 D. Chemstrip G – 1
C. Diastix – 2
42
The Uristix reagent strip can detect
glucose and protein only
43
The titratable acidity of a 24-hour urine collected in ice utilizes as titrant the
0.1N NaOH
44
Bacterial growth in urine specimen is characterized by all of the following except A. clouding that cannot be cleared by acidification B. clouding that can be removed by paper filtration C. marked alkaline shift to a pH > 8.0 D. marked unsuitability as sample for bacterial culture
B. clouding that can be removed by paper filtration
45
The most accurate means of determining the pH of urine samples is the A. blue and red litmus paper method B. pH meter with a glass electrode C. titratable acidity testing using a 24-hour urine sample (in ice) D. reagent strip using bromthymol blue and methyl red
B. pH meter with a glass electrode
46
The protein uromucoid is secreted by the cells in the distal tubular cells and ascending loop of Henle. It is highly associated with cast formation. It is also referred to as the
Tamm-Horsfall glycoprotein
47
The presence of Bence Jones protein the urine is suggestive of
Multiple myeloma
48
A hazy urine with high protein content collected after a heavy exercise is an example of
Functional proteinuria
49
To detect the kinds of protein in the urine, what is needed is
Electrophoresis
50
The catabolic products derived from lipids which can become potentially toxic are the
ketone bodies
51
When lipid is lost in the urine, many granular casts, fatty casts and oval fat bodies are found in the urine sediment. Oval fat bodies are actually
fat-laden renal tubular epithelial cells
52
Tubular pattern proteinuria is seen in all of the following conditions except A. Fanconi’s syndrome B. Pyelonephritis C. Wilson’s disease D. Nephrotic syndrome
D. Nephrotic syndrome
53
The tubular pattern proteinuria cannot be easily detected using reagent strip methods due to the type of protein involved – the low molecular weight proteins such as alpha-1-microglobulin, light-chain immunoglobulins and lysozymes. On the other hand, glomerular pattern proteinuria is detected because the protein involved is mainly
albumin
54
Type of proteinuria characterized by the excretion of 4 g. of protein /day is described as
heavy
55
Also referred to as orthostatic proteinuria is
postural proteinuria
56
Which substance may affect urinary pH testing?
protein
57
Which statement regarding protein testing is not true? A. Reagent strips are not sensitive in measuring globulins but sensitive to albumin. B. Both albumin and globulins can be precipitated using SSA and TCA. C. Reagent strips can be used in assessing the degree of proteinuria. D. Both reagent strips and SSA and TCA methods are for urine protein screening
C. Reagent strips can be used in assessing the degree of proteinuria.
57
Which statement regarding protein testing is not true? A. Reagent strips are not sensitive in measuring globulins but sensitive to albumin. B. Both albumin and globulins can be precipitated using SSA and TCA. C. Reagent strips can be used in assessing the degree of proteinuria. D. Both reagent strips and SSA and TCA methods are for urine protein screening
C. Reagent strips can be used in assessing the degree of proteinuria.
58
What substance in the urine is tested using the Kjeldahl method and Biuret reaction?
protein
59
Bence Jones protein is best detected in urine via
Protein electrophoresis
60
Which blood glucose level exceeds the renal threshold for glucose leading to glucosuria? A. 100 mg/dL B. 157 mg/dL C. 130 mg/dL D. 220 mg/dL
D. 220 mg/dL
61
Urine glucose testing serves to check endocrine function to diagnose the disease
Diabetes mellitus
62
The common thing about using reagent strips for glucose testing such as Clinistix, Multistix and Chemstrip is the
double sequential enzyme reaction
63
The copper reduction tablet test for glucose is the
Clinitest
64
What enzyme will oxidize glucose into gluconic acid and hydrogen peroxide?
glucose oxidase
65
The range of drops required of the urine sample in the glucose testing using Clinitest is
2 to 5
66
O-toluidine is the chromogen used in which reagent strip for glucose?
Clinistix
67
All of the following are reducing sugars except A. glucose B. fructose C. galactose D. sucrose
D. sucrose
68
If a pass through phenomenon happens in the glucose test using Clinitest, one should do A. retesting using lesser amount of urine sample B. recollection of urine sample and retesting glucose C. confirm the result using Benedict’s method D. no additional testing and results obtained can be reported
A. retesting using lesser amount of urine sample
69
In galactokinase deficiency, galactose cannot be converted to glucose. From what sugar was the galactose that appears in the urine derived?
lactose
70
Which of the following tests is the most specific for urinary glucose testing? A. Clinitest B. Clinistix C. Benedict’s test D. Copper reduction test
B. Clinistix
71
What compound of copper is colored red?
Cu2O
72
What method is best to measure the individual reducing sugars in urine?
Thin layer chromatography
73
What organic substances are products of incomplete lipid metabolism?
ketone bodies
74
The most abundant among these organic substances in the urine is
urea
75
The most abundant among these inorganic urine constituents is
chloride
76
Ketonuria may be seen in all of the following conditions except A. fasting B. type I diabetes mellitus C. excessive exercise D. carbohydrate-rich diet
D. carbohydrate-rich diet
77
Sodium nitroferricyanide reaction (Acetest) is specific for urinary
diacetate
78
Rothera’s wet method can detect all of the following except A. acetoacetic acid B. beta-hydroxybutyrate C. acetone D. ketone bodies
B. beta-hydroxybutyrate
79
The main ingredient of the Gerhardt’s test for the detection of urine diacetic acid is
ferric chloride
80
Which of the following substances is an oxidizing agent? A. ascorbic acid B. glutathione C. hydrogen peroxide D. uric acid
C. hydrogen peroxide
81
If delay in testing for ketone bodies cannot be prevented, the urine sample should be
refrigerated at 2-10 degrees Celsius
82
The Multistix reagent pad for blood uses of the chromogen tetramethylbenzidine which, in the presence of blood, causes a color change from
yellow to green
83
What red-brown pigment in the urine is produced after rhabdomyolysis?
myoglobin
84
Which of the following is not a breakdown product of hemoglobin? A. bilirubin C. hemosiderin B. amino acids D. haptoglobin
D. haptoglobin
85
The Diazo (p-nitrobenzenediazonium p-toluene sulfonate) tablet test is for the detection of urine
bilirubin
86
Ehrlich’s aldehyde reaction is the formation of reddish-brown color due to
urobilinogen
87
Bilirubin can be detected using all of the following methods except A. Ictotest C. Diazo reagent strip B. Yellow foam test D. Blondheim method
D. Blondheim method
88
Schwartz-Watson test differentiates between the presence of urobilinogen and
porphobilinogen
89
Inverse Ehrlich’s reaction is also known as
Hoesch’s test
90
A positive nitrite test indicates _________, while a positive leukocyte esterase test indicates ________
bacteriuria, pyuria
91
C-Stix reagent strips are impregnated with buffered phosphomolybdates to detect
ascorbic acid
92
The 5-hydroxyindole acetic acid (5-HIAA) is a byproduct of metabolism of
serotonin
93
If serotonin is derived from the amino acid tryptophan, melanin is derived from which amino acid?
tyrosine
94
Defects in the synthesis of heme moiety of hemoglobin would cause
porphyrias
95
What apparatus is required to detect the lavender to violet fluorescence of porphyrins after acidification of urine sample and addition of glacial acetic acid:ethyl acetate mixture?
Wood’s lamp
96
Which of the following has a peroxidase-like activity? A. hexokinase C. heme B. myoglobin D. hydrogen peroxide
C. heme
97
The most abundant among the ketone bodies which accounts 78% of the total in urine is A. acetone C. acetoacetic acid B. beta-hydroxybutyric acid D. urea
B. beta-hydroxybutyric acid
98
Which pathologic condition would cause a positive Acetest? A. diabetes mellitus C. diabetes insipidus B. nephrotic syndrome D. high fat diet
D. high fat diet
99
Which chemical parameter is not found in Multistix 10 SG? A. Urobilinogen C. Nitrite B. Ascorbic acid D. Leukocyte esterase
B. Ascorbic acid