Page 21 Flashcards
(32 cards)
Condensed nuclei in cells and massive mitochondria are features of
Irreversib cell injury
A patient has MI with 90% artery blockage. Which nuclear change indicates irreversible cell injury?
Karyorrhexis
What indicates irreversible damage to the nucleus?
Karyolysis
Cell shrinkage and cytoplasmic blebs are features of
Irreversible cell injury
What is the earliest observable sign of irreversible cell change in MI?
Contraction bands in cytoplasm
First observable sign of irreversible cell injury in a cardiac cell?
Contraction bands in the cytoplasm
What is a feature seen in cocaine-induced myocardial infarction?
Contraction band necrosis
What is characteristic of reversible cell injury?
Cellular swelling
What is an early sign of reversible cell injury?
ER swelling
What is one of the first structural changes in reversible ischemic cell injury?
Swelling of endoplasmic reticulum
What causes cell swelling in hypoxic injury?
Entry of extracellular water
What is the first sign of reversible cellular damage?
Ballooning or hydropic changes secondary to mitochondrial injury
What is a similarity between cardiac and skeletal muscle?
Transverse striations
Which feature is shared by skeletal and cardiac muscle fibers?
Contains T-tubules
Upon stimulation what protein does calcium bind to in skeletal muscle?
Troponin c
Which protein is important for contraction in skeletal but not smooth muscle?
Troponin
Which protein is utilized by skeletal muscle during relaxation?
Tropomyosin
Which muscle type is non-striated?
Smooth muscle
Which muscle is voluntary in action?
Skeletal muscle
Which muscle types are involuntary in action?
Cardiac and smooth muscle
Which muscle type has intercalated discs?
Cardiac muscle
Do skeletal and smooth muscles have intercalated discs?
No
Which muscle type contracts very rapidly?
Skeletalmuscle
Which muscle type contracts slowly?
Smooth muscle