Pain Flashcards

1
Q

What is Congenital Analgesia

A

The agony of feeling no pain

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2
Q

Why is pain a necessary evil

A

It acts as a protective mechanism

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3
Q

The heel stick

A

-preformed in the first 24 hours
-used to screen for health conditions
-painful experience for newborns

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4
Q

Racial disparities in preterm births

A

Black and indigenous babies are at a higher risk of preterm births and have a higher infant mortality rate

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5
Q

Drugs introduced between 1960 and 2009

A
  • 59 analgesic drugs introduced
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6
Q

Hypesthesia

A

Diminished capacity for physical sensation of pain

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7
Q

McGraw study on hypesthesia (1941)

A

-Identified the first 10 days of life as a period of hypesthesia
-Used 2000 pin prick observations
-Believed that newborns can’t interpret painful experiences due to lack of memory

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8
Q

Neural activity between adult and infant pain

A

-fMRI reveals neural overlap
-suggests that the infant pain experience closely resembles that seen in adults

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9
Q

History of analgesic use in neonates

A

-Neonates do feel pain
-insufficient scientific understanding of the brain meant that neonates were not offered pain relief, even for major surgeries

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10
Q

Characteristics of pain

A

Pain is unpleasant at both sensory and emotional levels, potentially but not necessarily associated with tissue damage, and subjectivity

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11
Q

How does pain differ between individuals

A

-pain is subjective
-with same stimulus some individuals will experience higher levels of pain than others
-uses visual analog scale (VAS) to measure pain

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12
Q

Sex differences in pain sensitivity

A

females are more sensitive to pain

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13
Q

Def: measurement error

A

the degree to which the obtained pain measure fails to reflect the actual pain experience

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14
Q

How can emotional association to pain affect verbal ratings and what are the implications of this

A

-can cause inflated verbal ratings
-may lead to catastrophizing for better care
-caregivers must trust patient is accurately conveying their pain
-those who cannot express pain verbally may suffer

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15
Q

Facial expressions which reveal pain

A

-Nose broadened and bulging
-mouth open and squarish
-checks raised
-eyes squeezed shut
-forehead brow bulge
-brows low and drawn together

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16
Q

Crying that is characteristic of pain

A

increased pitch and increased rhythmic sound

17
Q

Pain in neonates and stress response

A

-Pain in neonates elicits a stress response
-circumcision without anesthetic increases crying and cortisol levels

18
Q

Non-verbal responses to pain

A

-facial expression
-crying characteristics
-cortisol levels
-neural activity

19
Q

Hair receptor follicle

A

-located on surface of hair shaft
-detect light brush
-Adaption rate: rapid

20
Q

Meissner corpuscle

A

-located in between the epidermis and dermis
-detect movement (dynamic deformation)
-Adaption rate: rapid

21
Q

Pacinian corpuscle

A

-Located deep in the dermis
-Detects vibration
-Adaption rate: rapid

22
Q

Merkel’s disk

A

-Location between dermis and epidermis
-detects indentation depth
-Adaption rate: moderate

23
Q

Ruffini corpuscle

A

-located in dermis
- detects stretch
-Adaption rate: moderate

24
Q

Free nerve endings

A

-located at the base of the dermis
-detects injurious forces
-Nociceptor
-Adaption rate: slow
-higher activation threshold than mechanoreceptors

25
Q

A-beta Fibers

A

-Touch
-myelinated
-6 to 2 um
-35 - 90 m/s

26
Q

A-delta Fibers

A

-Pain (mechanical and thermal)
-myelinated
-1-5 um diameter
-1 -40 m/s

27
Q

C fibers

A

-majority of nociceptors
-Pain ( mechanical, thermal and chemical)
-non-myelinated
-0.2 - 1.5 um
-0.5 - 2 m/s

28
Q

How are peripheral pain signals transmitted to the brain?

A

-Specific part of the body is sent to a specific section of the spinal cord
-Enters spinal cord through dorsal horn and synapses with the spinothalamic tract
-crosses midline and travels up spinal cord
-synapses in the thalamus and then is directed to somatosensory cortex

29
Q

How are peripheral mechano signals transmitted to the brain

A

-Enters through dorsal horn and travels up the spinal cord to the medulla oblongata
-synapses in medulla and crosses midline
-Synapses in thalamus and then goes to somatose cortex