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NAPLEX STUDY > Pain > Flashcards

Pain Flashcards

1
Q

acetaminophen + hydrocodone

A

Lorcet, Lortab, Norco, Vicodin

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2
Q

acetaminophen + oxycodone

A

Endocet, percocet

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3
Q

acetaminophen + codeine

A

tylenol 2, 3, 4

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4
Q

acetaminophen + caffiene

A

excedrin tension headache

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5
Q

acetaminophen + aspirin + caffiene

A

excedrin extra strength

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6
Q

acetaminophen + caffiene + pyrilamine

A

midol complete

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7
Q

tylenol max dose

A

4 g

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8
Q

pediatric tylenol dose

A

10-15 mg/kg/day

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9
Q

acetaminophen overdose

A

-antidote: N-acetylcystiene
-administered intravenously or orally
-Rumack-Matthew nomogram

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10
Q

NSAIDs and third trimester

A

DO NOT USE - can prematurely close the DA

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11
Q

Celecoxib (Celebrex)

A

contraindicated in sulfa allergy

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12
Q

salicylate over dose

A

tinnitus

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13
Q

Kadian (morphine), Nucytna ER, oxymorphone ER, and Zohydro ER (hydrocodone ER)

A

do not consume alcohol with this medication. Alcohol can cause increased drug plasma levels, which can lead to potentially fatal overdose

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14
Q

Fentanyl

A

-not for opioid naive patients –> must have equivalent of morphine 60 mg/day or more for at least 7 days

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15
Q

morphine

A

10 mg IV/IM = 30 mg oral

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16
Q

hydromorphone

A

1.5 IV/IM = 7.5 mg oral

17
Q

opioid allergy

A
  • common drugs in the same chemical class that cross react with each other have COD or MORPH in the name (besides buprenoprhine)
    -CODeine, hydroCODone, oxyCODone, MORPHine, hydroMORPHone, oxyMORPHone, bupreNORPHine
18
Q

treatment of opioid-induced constipation

A

methylnaltrexone (Relistor), Naloxegol (Movantik), Lubiprostone (Amitiza)

19
Q

central acting analgesics

A

tramadol and tapentadol (Nucynta)
-lower the seziure threshold
-caution with serotonergic drugs `

20
Q

FDA approved for OUD

A

buprenorphine

21
Q

SNRIs and TCAs used for pain

A

amitriptyline and duloxetine

22
Q

carisoprodol (soma)

A

C IV
-antispasmodic

23
Q

Triptan formulations

A

-ODT: Rizatriptan, Zolmitriptan
-nasal spray: sumatriptian, zolmitriptan
-powder: sumatriptian
-SC inj (prefilled syringes): sumatriptian
-SC inj (autoinjector): sumatriptian

24
Q

Triptan contraindications

A

cardiovascular disease, uncontrolled HTN, ischemic heart disease
-do not use within 24 hours of another triptan or ergotamine-type medication

25
Q

triptan warnings

A

increase blood pressure, serotonin syndrome

26
Q

triptan side effects

A

paresthesia (tingling/numbness)
-triptan sensations

27
Q

triptans for children and adolescents

A

almotriptan tablets, zolmitriptan nasal spray and Treximet in children > 12 YOA

rizatriptan 6-17 YOA

28
Q

Frovatriptan

A

longest half life

29
Q

ergotamine

A

-used in those who do not benefit from triptans
-Dihydroergotamine (DHE 45): inj, nasal spray
-serious and life-threatening peripheral ischemia from potent CYP3A4
-CI: uncontrolled HTN, pregnancy, ischemic heart disease

30
Q

other migraine medication

A

rimegepant (Nurtec ODT)
Ubrogepant (Ubrelvy)
Lasmiditan (Reyvow) - CV

31
Q

prophylactic migraine drugs

A

propranolol, metoprolol, divalproex, topiramate

32
Q

drugs that increase uric acid

A

ASA
calcineurin inhibitors
diuretics (loops and thiazides)
Niacin
pyrazinamide
select chemotherapy agents
select pancreatic enzyme products

33
Q

gout tx

A
  1. Colchicine, steroids (prednisone/prednisolone, methylprednisolone), NSAIDs (indomethacin, naproxen, celebrex)
  2. chronic tx: XOI - allopurinol or febuxostat
    3: if XOI does not work and UA > 6: add on probenecid or lesinurad to daily XOI or replace XOI with IV pegloticase
34
Q

colchicine gout dose

A

1.2 mg PO followed by 0.6 mg in 1 hour (do not exceed a total of 1.8 mg in 1 hour or 2.5 mg/day)

35
Q

allopurinol

A

-hypersensitivity rxn - including SJS/TEN, DRESS
-HLA-B*5801 testing prior to use

NAPLEX STUDY (25 decks)

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