Pain Physiology Flashcards
(46 cards)
A patient states that they have 8/10 pain in their abdomen. Nurse Karen assessess the patient and believes that the patients is full of caca and is lying about their condition. As a nurse, what should Karen know?
- Pain in a personal/individual experience
- pain exists wherever/whatever the patient says it
What is pain?
- an unpleasant sensory and emotional experience associated with actual or potential tissue damage
Explain the pain pathway
- Transduction – Activation of pain receptors, converts stimuli to electrical impulses.
- Transmission – pain signals from spinal cord travel to brain (CNS)
- Perception – Recognition and interpretation of pain
-
Modulation – Body adjust to pain response; send inhibitory signals to spinal cord
-> Endogenous opioids inhibit release of substance P ➡ reduces pain
-> Endorphins: body’s natural pain reliever
-> Enkephalins: less potent; widespread; reduce pain
What does Substance P do?
- continues the pain signal from the spinal cord to the brain
What is the general effect of endogenous opioids/neurotransmitters? What are examples of endogenous opioids/neurotransmitters?
- Inhibit the release of Substance P
Examples:
- Endorphins
- Ekephalins
What are Endorphins?
- the body’s natural pain reliever
What are Enkephalins?
- less potent, pain reliever
-> for widespread pain
Describe the Mechanisms of Pain Tranmission
- Tissue damage → release of pain mediators
- Bradykinin: causes pain & swelling
- Histamine: causes swelling & redness
- Potassium: stimulate nociceptors
- Prostaglandins: make pain feel worse
- Serotonin: modify pain (⬆ or ⬇)
- Pain mediators activate nociceptors
- A-Delta Fibers: Long, Myelinated, rapid transmission → sharp, well defined pain
- C Fibers: Short, Unmyelinated, slow transmission → dull, poorly localized pain
- Signal from fibers travel to spinal cord
- Spinal cord stimulate release of:
- Substance P: continue the pain signal to the brain
- Endogenous opioids/neurotransmitters
-> Endorphins
-> Enkephalins
What does Bradykinin cause?
- pain
- swelling
What do Histamines cause?
- swelling
- redness
What does Potassium do?
- stimualte nocicpetors
What do Prostaglandins do?
- pain
- inflammation
- block clot aggregation
What does Serotonin do?
- modify pain (↑ or ↓ pain)
Describe the following type of nerve fiber:
A-Delta
(Size, Myelin Sheath?, Conduction Speed, Type of Pain)
Size:
- Large
Myelin Sheath?
- Myelinated
Conduction Speed:
- Rapid transmision
Type of Pain:
- sharp & well localized
Describe the following type of nerve fiber:
C fibers
(Size, Myelin Sheath?, Conduction Speed, Type of Pain)
Size:
- Small
Myelin Sheath?
- Unmyelinated
Conduction Speed:
- Slow
Type of Pain:
- dull & nonlocalized
What does the Gate Theory of Pain suggest?
- the Nervous System processess limited imput at a time
What is the premise of the Gate Control Theory of Pain?
- Pain impulses (thin nerve fibers) compete with sensory input (large fibers like pressure, heat/cold) for brain recognition
What happens when large sensory fibers are activated?
- it closes the gate for thin nerve fibers, allowing large nerve fibers to come in
-> decreases pain
What is an example of a method that uses the Gate Control Theory of Pain?
- Transcutaneous Electrical Nerve Stimulation (TENS).
A patient reports chronic back pain. The nurse applies a TENS unit which sends mild electrical impulses to the area. After a few minutes, the patient says the pain feels less intense. According to the Gate Control Theory of Pain, what is the reason for this?
- electrical stimulation activates large nerve fibers, closing the gate to thin pain fibers, decreasing the perception of pain.
Describe the following pain duration:
Acute Pain
(Physiology?, How long does it last?, Treatability, Onset, Localized or Generalized, Effects on the Body, Examples)
Examples: MAD BBLS
Physiology:
- warning signals by activating SNS
-> cause physiologic responses
How long does it last?:
- usually temporary (< 3 months)
Treatability:
- Easy to treat
Onset:
- Sudden onset
Localized or Genralized:
- Localized
Efects on the Body:
- activate fight or fligt
-> sweating & dilated pupils - ↑ VS
-> BP, HR, RR
Examples
- MI
- Appendicitis
- Dental procedure
- Burns/cuts
- Broken bones
- Labor/childbirth
- Surgery
Describe the following pain duration:
Chronic Pain
(Physiology?, How long does it last?, Treatability, Onset, Localized or Generalized, Effects on the Body, Examples)
Examples: CC DR P
Physiology:
- results from CNS dmg
-> cause sometimes unclear
How long does it last?:
- > 3 months
Treatability:
- Difficult to treat
-> persistent/recurring
Onset:
- Gradual onset
Localized or Genralized:
- Both (character/quality changes over time)
-> dull/persistent aching
Efects on the Body:
- ↓ VS or stable
-> BP, HR, RR
Examples
- Crohn’s dz
- Cancer pain
- Diabetes
- Rheumatoid Arthritis
- Procedural pain (chronification)
What does localized pain mean?
- pain confined to specific area
What does gernalized pain mean?
pain felt in larger area of the body or the entire body