Pancreas

Question 1

Part of pancreas that secretes digestive enzymes and bicarbonate

Answer 1

head

Question 2

Part of pancreas that secretes insulin and glucagon

Answer 2

body

Question 3

Part of pancreas that produces digestive enzymes and insulin

Answer 3

tail

Question 4

Fecal elastase in chronic pancreatitis

Answer 4

<200

Question 5

Pancrelipase (Creon) dose (pancreatic insufficiency, chronic pancreatitis)

Answer 5

10,000 - 25,000 lipase units/meal

Question 6

Cells that make up the exocrine pancreas

Answer 6

acinar cells

Question 7

Cells that make up the endocrine pancreas

Answer 7

islets of Langerhans

Question 8

Hormones secreted by the islets of Langerhans (3)

Answer 8

insulin, glucagon, somatostatin

Question 9

Gene testing for suspected hereditary pancreatitis (2)

Answer 9

CFTR gene (cystic fibrosis)
PRSS1 (hereditary pancreatitis)

Question 10

Most common cause of hereditary pancreatitis

Answer 10

PRSS1 gene mutation

Question 11

PRSS1 mutation inheritance pattern

Answer 11

autosomal dominant

Question 12

Chemo options for pancreatic cancer (2)

Answer 12

FOLFIRINOX
gemcitabine

Question 13

Lipase level diagnostic for pancreatitis (factor of ULN and rough number)

Answer 13

3x ULN, ~400 (ULN is around 140)

Question 14

Stool elastase diagnostic for pancreatic insufficiency

Answer 14

< 200 ug/g

Question 15

Early fluid resuscitation amount for pancreatitis

Answer 15

20-30 mL/kg

Question 16

Ranson’s criteria (initial) (5)

Answer 16

age > 55
WBC > 16,000
BG > 200
LDH > 350
AST > 250

Question 17

Indications for drainage of a pancreatic pseudocyst (3)

Answer 17

1) > 6 cm
2) symptomatic
3) or infected

Question 18

Preferred fluid and rate for acute pancreatitis treatment

Answer 18

LR @ 250-500/hr

Question 19

Fecal elastase indicative of exocrine insufficiency

Answer 19

< 200

Question 20

Most common portion involved w/ pancreatic cancer

Answer 20

head

Question 21

Most common portion involved w/ pancreatitis

Answer 21

head

Question 22

Medication that reduces pancreatic secretions

Answer 22

octreotide

Question 23

Most common region for pancreatitis and pancreatic cancer

Answer 23

pancreatic head

Question 24

Function of pancreatic head

Answer 24

secretes digestive enzymes and bicarb into the duodenum

Question 25

Function of pancreas body

Answer 25

secrete insulin and glucagon

Question 26

Function of pancreas tail

Answer 26

produce digestive enzymes and insulin

Question 27

Exocrine parts of pancreas (2)

Answer 27

acinar cells ducts

Question 28

Exocrine secretion of pancreas (2)

Answer 28

digestive enzymes (acinar cells) bicarb (ducts)

Question 29

Endocrine part of pancreas (1)

Answer 29

islets of Langerhans

Question 30

Secretion from islets of Langerhans (3)

Answer 30

insulin glucagon somatostatin

Question 31

Risk factors for pancreatic cancer (4)

Answer 31

smoking family hx chronic pancreatitis diabetes

Question 32

Amylase function

Answer 32

breaks down carbohydrates

Question 33

Genetic testing for hereditary pancreatitis (2)

Answer 33

CTFR gene PRSS1

Question 34

Fecal elastase in pancreatic insufficiency

Answer 34

decreased

Question 35

Creon dose

Answer 35

10,000-25,000 IU per meal

Question 36

Chemotherapy for pancreatic cancer (2)

Answer 36

FOLFIRINOX gemcitabine

Question 37

Enzyme that is a marker of pancreatic exocrine function

Answer 37

amylase

Question 38

Age in Ranson's criteria

Answer 38

> 55

Question 39

WBC in Ranson's criteria

Answer 39

> 16,000

Question 40

BG in Ranson's criteria

Answer 40

> 200

Question 41

LDH in Ranson's criteria

Answer 41

> 350

Question 42

AST in Ranson's criteria

Answer 42

> 250

Question 43

Fluid quantity for acute pancreatitis

Answer 43

20-30 mL/kg

Question 44

Percentage of patients w/ acute pancreatitis w/ pseudocyst

Answer 44

10-20%

Question 45

Indications for pancreatic pseudocyst drainage (3)

Answer 45

> 6 cm symptomatic infection

Question 46

LR rate for pancreatitis

Answer 46

250-500 mL/hr

Question 47

Ranson score indicating severe disease

Answer 47

>/= 3