Pancreas

Question 1

What are the three criteria for making diagnosis of acute pancreatitis?

Answer 1

1. Epigastric pain
2. Elevated amylase and lipase x3 N
3. CT showing abnormal pancreas

Question 2

What are the drugs that can lead to acute pancreatitis?

Answer 2

Sulfa drugs
NRTIs
Protease Inhibitors
GLP-1 agonists Exinetide and liraglutide (anti diabetic)
6-MP (mercaptopurine) (chemo)

Question 3

At which level of triglycerides the risk of acute pancreatitis is very high

Answer 3

More than 1000 mg/dl

Question 4

What are the two important and frequent causes of acute pancreatitis?

Answer 4

Gall stones
Alcohol consumption

Question 5

What is the key enzyme which triggers the whole path of physiology of acute pancreatitis?

Answer 5

Trypsin

Question 6

What are the major causes of SIRS severe inflammatory response syndrome?

Answer 6

Trauma
Acute pancreatitis
Septic shock

Question 7

What are the criteria for diagnosing SIRS?

Answer 7

HRTW
HR >90
RR >20
T >38.3 or < 36
WBC >12000

Question 8

What is the key histological feature of pseudo cyst of pancreas?

Answer 8

Lined by granulation tissue
No epithelium
No necrosis

Question 9

What are the major complications of pseudocyst of pancreas?

Answer 9

Rupture peritonitis
Fistula
Abscess formation

Question 10

What is the mineral abnormality seen in patients with complicated acute pancreatitis?

Answer 10

Hypocalcemia
Hypomagnasemia

Question 11

What is the key lab finding unique to auto immune acute pancreatitis?

Answer 11

Increased IgG4 levels with IgG4 positive plasma cells