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Flashcards in pancreas quiz 5 Deck (22):
1

What is the #1 cause of acute pancreatitis?

gallstones (more common in women)

2

#1 cause of chronic pancreatitis?

alcohol (this is more common in men)

3

labs for pancreatitis?

serum amylase and lipase 3 times higher than normal

4

chronic pancreatitis

shrinks, fibrotic, fat necrosis

5

what is most common type of pancreatic cancer?

pancreatic adenocarcinoma

6

where does pancreatic adenocarcinoma arise from?

exocrine portion of pancreas
99% from pancreatic ducts
1% from acinar cells

7

what is prognosis for pancreatic cancer?

bad
4th most common cause of death from cancer worldwide

8

sequelae of acute/chronic pancreatitis?

pancreatic pseudocyst
infected necrosis
pancreatic abscess (infected pseudocyst)

9

pancreatic pseudocyst

cyst in pancreas with fibrous capsule
- high concentration of pancreatic enzymes
- no epithelial lining on inside (no true epithelium)

10

pancreatic abscess

infected pseudocyst or fibrous wall forms around fluid collections
- could rupture
- infected with gut bacteria

11

where would be the worst area of pancreas to have a problem?

posterior inferior

12

What area are you more likely to diagnose early with pancreas?

problems in head of pancreas because it causes earlier jaundice

13

what can chronic pancreatitis lead to?

diabetes
increases risk for pancreatic cancer

14

what bugs does pancreatic abscess contain?

e. coli, klebsiella, pneumoniae, etc

15

malignant tumors of exocrine pancreas?

pancreatic adenocarcinoma
mucinous cystadenocarcinoma

16

pseudopapillary tumors

benign
solid
well-demarcated
hemmorhagic on cut sections
associated mostly with women

17

hist of pseudopapillary tumors

sheets of cells
uniform nuclei
cystic areas between tumor cells = "pseudo papillae"
PAS positive eosinophilic cytoplasmic inclusions

18

most frequent cystic tumors of pancreas and 50% of all cystic tumors

mucinous cystadenoma

19

second most common cystic tumor of pancreas. Honeycombed appearance. Benign

Serous cystadenoma

20

What syndrome is are serous cyst adenomas associated with?

von-hippel-lindau syndrome: genetic condition with cysts in pancreas, liver, kidney and hemangiblastomas in cerebellum, spinal cord, etc

21

what is pancreatic adenocarcinoma associated with?

Trousseau's syndrome of hyper coagulability

22

Does pancreatic adenocarcinoma affect endocrine system?

It is in ducts so it doesn't effect endocrine function.