Gallbladder Quiz 5 Flashcards Preview

Path III Quizzes > Gallbladder Quiz 5 > Flashcards

Flashcards in Gallbladder Quiz 5 Deck (27):
1

Congenital biliary atresia

common bile duct is blocked or terminates/is absent
see liver sx in children such as itching, malabsorption, eventual cirrhosis and portal HTN.

2

choledocal cysts

congenital cystic dilations of common bile duct

3

cholelithiasis

stones in gallbladder, bile duct, pancreatic duct, ampulla

4

choledocolithiasis

stones in common bile duct

5

what causes more of a risk cholelithiasis or choledocolithiasis? And why?

choledocolithiasis because the stones can block the liver, gallbladder, and pancreas.

6

when does acquired biliary atresia occur?

autoimmune disease and causes chronic rejection of transplanted liver allograft

7

treatment for congenital biliary atresia?

surgical anastomosis or transplant

8

what are sx of choldedocal cyst?

jaundice and clay colored stools

9

what are the most common causes of cholecystitis?

escherichia coli
bacteroides

10

what causes acute cholecystitis?

cholelithiasis: blockage of cystic duct

11

cholesterol stones

>80% cholesterol by weight
most common (90% of all stones)

12

pigment stones

< 20% cholesterol
show up on x-ray due to ca
small dark stones

13

mixed stones

20-80% cholesterol
possibly visible on X-ray depending on ca level

14

cholesterolosis

- abnormal deposition of cholesterol in gallbladder wall
- thickened wall
- cholesterol stones seen at times

15

what is cholesterolosis associates with?

chronic cholecystitis
and sometimes cholelithiasis

16

hist of cholesterolosis?

strawberry gallbladder
bright yellow dots on mucosal surface

17

hist of chronic cholecystitis

Rokitansky-Aschoff sinuses in muscularis layer: pockets in wall of muscularis layer

18

porcelain gallbladder

calcified by persistent inflammation due to presence of stones
- outlined in thin white ring on X-ray

19

what is a concern with porcelain gallbladder?

gallbladder cancer

20

what is a bad sequelae of choledocolithiasis?

risk of ascending cholangitis of bacteria in colon ascending to liver via ductal system
- life threatening
- happen more often in the presence of gallstones (70-90%)

21

hist of ascending cholangitis

onion skin fibrosis of duct
- indistinguishable from that seen in PSC

22

cholangitis

inflammation of duct

23

what are risk factors for gallbladder carcinoma?

chronic cholecystitis
chronic cholelithiasis
obesity

24

#1 type of gallbladder cancer

adenocarcinoma
- glandular origin and malignant

25

hist of gallbladder carcinoma

more mitotic figures
greater nucleus to cytoplasm ratio

26

Risk factors for carcinoma of extra hepatic bile ducts

UC
choledocal cyst
parasites
gallstones

27

what type of cells are seen in intestinal type andenocarcinoma of the gallbladder?

lots of goblet cells