Flashcards in Gallbladder Quiz 5 Deck (27):
Congenital biliary atresia
common bile duct is blocked or terminates/is absent
see liver sx in children such as itching, malabsorption, eventual cirrhosis and portal HTN.
congenital cystic dilations of common bile duct
stones in gallbladder, bile duct, pancreatic duct, ampulla
stones in common bile duct
what causes more of a risk cholelithiasis or choledocolithiasis? And why?
choledocolithiasis because the stones can block the liver, gallbladder, and pancreas.
when does acquired biliary atresia occur?
autoimmune disease and causes chronic rejection of transplanted liver allograft
treatment for congenital biliary atresia?
surgical anastomosis or transplant
what are sx of choldedocal cyst?
jaundice and clay colored stools
what are the most common causes of cholecystitis?
what causes acute cholecystitis?
cholelithiasis: blockage of cystic duct
>80% cholesterol by weight
most common (90% of all stones)
< 20% cholesterol
show up on x-ray due to ca
small dark stones
possibly visible on X-ray depending on ca level
- abnormal deposition of cholesterol in gallbladder wall
- thickened wall
- cholesterol stones seen at times
what is cholesterolosis associates with?
and sometimes cholelithiasis
hist of cholesterolosis?
bright yellow dots on mucosal surface
hist of chronic cholecystitis
Rokitansky-Aschoff sinuses in muscularis layer: pockets in wall of muscularis layer
calcified by persistent inflammation due to presence of stones
- outlined in thin white ring on X-ray
what is a concern with porcelain gallbladder?
what is a bad sequelae of choledocolithiasis?
risk of ascending cholangitis of bacteria in colon ascending to liver via ductal system
- life threatening
- happen more often in the presence of gallstones (70-90%)
hist of ascending cholangitis
onion skin fibrosis of duct
- indistinguishable from that seen in PSC
inflammation of duct
what are risk factors for gallbladder carcinoma?
#1 type of gallbladder cancer
- glandular origin and malignant
hist of gallbladder carcinoma
more mitotic figures
greater nucleus to cytoplasm ratio
Risk factors for carcinoma of extra hepatic bile ducts