Paper 2 , One Words

Question 1

Ames test

Answer 1

Detect mutagenicity

Question 2

Zinc dependent enzymes

Answer 2

Carbonic anhydride
Carboxypeptidase
Alkalin phosphatase

Question 3

Applications of pcr

Answer 3

Diagnosis of bact and viral diseases
Medicolegal
Genetic disorders detection
Prenatal diagnosis of inherited
Cancer
Fossil

Question 4

Klenow fragment

Answer 4

DNA Poly -I without 5’ -3’ exonuclease domain

Question 5

Korenberg enzyme

Answer 5

DNA Polymerase I

Question 6

Prostate cancer tumour marker

Answer 6

PSA
ACP
GGT

Question 7

Gene therapy vectors

Answer 7

Retroviruses
Adenoviruses
Herpes simplex viruses
Adeno associated renal virus vectors

Question 8

Frame shift mutations

Answer 8

Thalassemia
Premature chain termination
Run -on polypeptide

Question 9

Xeroderma pigmentosa

Answer 9

Nucleotide excision repair disorder
Defective formation of thymidine divers

Question 10

Type of collagen in connective tissues including bones

Answer 10

Type I

Question 11

Inhibitor of both prokaryotic and eukaryotic translation

Answer 11

Puromycin

Question 12

Epstein Barr Virus

Answer 12

Nasopharyngeal carcinoma
Burkitts lymphoma

Question 13

Onco suppressor gene in the short arm of chromosome 17

Answer 13

P53

Question 14

RNAP 2 is inhibited by

Answer 14

alpha amanitin

Question 15

In ECF the most important buffer is

Answer 15

Bicarbonates

Question 16

Most important buffer in intercellular fluid

Answer 16

Phosphate

Question 17

Bromosulphthalein BSP due to assess

Answer 17

Excretory function of liver

Question 18

Serum calcitonin marker for

Answer 18

Medullary carcinoma of thyroid gland

Question 19

Radio iodine uptake studies uses what

Answer 19

I-131

Question 20

Presence of urobilinogen in urine represents

Answer 20

Haemolytic jaundice

Question 21

Chain breaking anti oxidants

Answer 21

SOD
Uric acid
VIT c

Question 22

Basement membrane with connective tissue

Answer 22

Type IV

Question 23

Type 1 collagen

Answer 23

connective tissue including bones

Question 24

Type 7 collagen

Answer 24

Anchoring fibrils

Question 25

Serum level of sodium

Answer 25

135-145 mol/L

Question 26

Potassium level in serum

Answer 26

3.5 - 5.0 mmol/l

Question 27

Gratuitous inducer

Answer 27

Isopropyl thiogalactoside

Question 28

De Ritis ratio

Answer 28

AST /ALT

Question 29

Rf value

Answer 29

Distance travelled by the solute / distance travelled by the solvent

Question 30

Bence Jones proteins

Answer 30

Monoclonal light chains produced by plasmacytoma

Question 31

Storage form of iron

Answer 31

Ferritin binds to ferric ions

Question 32

Transport form of iron

Answer 32

Transferrin

Question 33

Oncogenes

Answer 33

ras src sis

Question 34

Oncosuppressor genes

Answer 34

Retinoblastoma RB Wilms tumour WT Familal adenomatous polyposis FAP deleted in colon cancer DCC

Question 35

Drug used for post menopausal breast cancer

Answer 35

Tamoxifen

Question 36

Enzymes used as labels in ELISA

Answer 36

Alkaline phosphatase Horseradish peroxidase