Part 2 Flashcards

1
Q

platelets help in the repair of a damaged vessel wall by releasing what substance

A

growth factor

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2
Q

normally what prevents platelets from adhering to a normal endothelium

A

glycoproteins in the platelet wall

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3
Q

what function does thromboxane A2 play in activation of platelets

A

potentates platelet granule release

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4
Q

what is not a function of prostacyclin

A

acts as a vasoconstrictor

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5
Q

how does aspirin block the formation of both thromboxane A2 and prostacyclin production

A

blocks FA cyclooxygenase

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6
Q

which is capable of dissolving or liquifying a blood clot

A

plasmin

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7
Q

how does dicumarol function as an anticoagulant

A

inhibits liver clotting factors

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8
Q

what is the cause of a repercussion injury in the myocardium

A

free radical damage

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9
Q

what effect will occur if fast Na channels in a cardiac cell is blocked

A

the cell will depolarize at a slower rate

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10
Q

if EDV is 150 mL and ESV is 100 mL, what is the ejection fraction

A

33%

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11
Q

during isovolumic contraction to the left-sided valves are in what state

A

mitral closed, aortic open

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12
Q

most of the blood ejected from the ventricles is ejected in the first half of the ejection phase

A

true

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13
Q

what percent of blood that moves from atria to ventricles is actively pumped by the atria

A

25%

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14
Q

what is the major function of the AV node

A

delay the wave of depolarization from entering the ventricles

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15
Q

the stable resting polarized state in a typical cardiac muscle cell is due to

A

K at its Nernst equilibrium and an impermeable membrane to Na and Ca

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16
Q

under resting conditions, what % of oxygen is being extracted fro the arterial blood that is perfusing the myocardium

17
Q

how does digitalis act to increase strength of contraction

A

decreases function of calcium exchange protein

18
Q

the first heart sound is associated with what event

A

closure of the AV valves

19
Q

a machinery murmur heard throughout the entire cardiac cycle is likely associated with what condition

A

patent ductus arteriosis

20
Q

a machinery murmur heard throughout the entire cardiac cycle is likely associated with what condition

A

patent ductus arteriosis

21
Q

a diastolic murmur would likely be associated with what condition

A

aortic insufficiency

22
Q

as systemic arterial blood pressure is increased, what happens to the strength of left ventricular contraction if the ANS effect on the heart is blocked

A

decrease in LV contractile strength

23
Q

what is the function of the papillary muscles in the wall of the RVs when they contract

A

prevents prolapse of the tricuspid valve

24
Q

which are dependent on ANS function

A

pressure induced homeometric autoregulation

25
how does the stretch on the SA nose increase HR
by increasing membrane permeability to Na/Ca
26
increase EC K levels 2-3X above normal will have what effect on myocardial performance
extreme weakness and flaccidity
27
what effect would a fever of 100 degrees F have on resting HR
increased HR 10 bpm
28
most of the energy consumed by the heart is associated with
the production of heat
29
the principal energy source for cardiac output is
FAs
30
increased stretch on the ventricular myocardium at the end of diastole is associated with
increase calcium influx
31
PSNS activation can cause inhibition of NE release presynaptically
true
32
what is most responsible for the all or none response of the cardiac myocardium
intercalated discs
33
what is not a feature of the SA node
stable resting polarized state
34
in a third degree AV block, what is true
the atria and ventricles are beating independently
35
describe atrial repolarization
buried in the QRS complex
36
what normally prevents cells other than SA nodal cells from firing spontaneously
purkinje cells
37
if the net deflection of the QRS complex in lead I is negative 5 mm, and the net deflection in lead AvF is positive 5 mm, what can you say about the mean electrical axis
right axis deviation