Parturition Flashcards

1
Q

Parturition

A

Begins when fetal size and nutritional demands exceed what the placenta can do

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2
Q

Describe the entire process of parturition.

A

-Fetal stress -> Increase in ACTH -> Increase in fetal cortisol -> increase in enzymes (enzymes cause placental P$ to convert to E2) and PGF2a
-E2 -> increase secretion by female reproductive tract -> lubrication
-E2 and PGF2a -> increased myometrial contractions -> increase pressure -> increase cervical stimulation -> increase oxytocin -> results in maximum pressure
-PGF2a -> causes luteolysis
-PGF2a -> increases relaxin -> causes pelvic ligament stretching and cervical softening

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3
Q

Know the 3 enzymes that are altered by cortisol for conversion of progesterone to estrogen.

A

-17a-hydroxylase
-17-20 desmolase
-aromatase

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4
Q

Know how the orientation of the fetus changes as parturition approaches and why this is important

A

-fetus moves where face and front feet exit first
-Failure to do this results in breech and may cause dystocia

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5
Q

Know the general distribution of prenatal losses

A

-2/3 occur in the embryonic stage
-1/3 occur in the fetal stage

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6
Q

Stage 1 of labor

A

-Preparative stage
-myometrial contraction
-abdominal discomfort
-contraction uterus pushes fetus towards the cervix
-cervix is dilating and the fetus is pushed into the cervical canal

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7
Q

Stage 2 of labor

A

-Expulsion of Fetal stage
-strong uterine and abdominal contractions are occurring
-animal is usually recumbent and straining
-Relaxin takes effect
-estradiol results in higher mucus production that lubricates the tract and washed away the cervial seal of pregnancy
-fetus puts pressure in the fetal membranes and allantochorion eventually breaks and allantoic and amniotic fluid are lost. These fluids further lubricate the cervix and vagina
-this movement cases more intense contraction until the neonate is born

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8
Q

Stage 3 of labor

A

-expulsion of the placenta stage
-weaker myometrial contraction continue
-uterine contractions
-chorionic villi loosen
-expulsion of placenta
-delayed in ruminants due to presence of cotelydons separating independently
-suckling induces oxytocin release which triggers further uterine contractions

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9
Q

Be able to define and describe dystocia including some factors that cause it

A

-Dystocia: Difficult birth
-Happens due to excessive fetal size (cattle), abnormal presentation, or multiple births
-Factors: maternal health, mechanical issues, or fetal size/position

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10
Q

Maternal causes

A
  1. uterine inertia primary or secondary
  2. cervical spasm, incomplete dilation
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11
Q

Mechanical causes

A
  1. fetopelvic disproportion
  2. uterine torsion
  3. stenosis of cervix and vagina
  4. congenital anomalies
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12
Q

fetal causes

A
  1. abnormal presentation, position and posture
  2. development defects
  3. oversize fetus, twins
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13
Q

What can dystocia cause

A
  1. premature labor
  2. prolonged labor
  3. arrest of labor
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14
Q

Be able to define retained placenta

A

-Failure of the placenta to be expelled following birth
-If placenta is not expelled within 24 hours it may be retained for 5-6 days
-most common in cattle

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15
Q

What are the causes of a retained placenta

A

-lack of blood flow to chorionic villi and this causes them to regress
-High incidence in premature or early delivery
-high milk producers
-twins
-dystocia
-induction of parturition
-nutritional deficiencies of vitamin A or selenium

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16
Q

How is a retained placenta treated

A

-manual removal, but not recommended
-daily antibiotics
-large single antibiotic bolus
-oxytocin or PGF

17
Q

What are the major concerns of a retained placenta in humans and mares

A

-can cause death of mother from septicemia

18
Q

Know how pressure on the cervix during parturition hastens birth

A

-positive feedback loop
-fetus press on cervix
-afferent neurons coming from the cervix to the spinal cord sense the pressure on the cervix
-message is sent to hypothalamus (direct communication with the hypothalamus) that will affect the posterior pituitary gland to secrete more oxytocin