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Parvoviridae - Porcine Parvovirus (PPV) Flashcards

(15 cards)

1
Q

What are the manifestations of the disease described by?

A
SMEDI
Stillbirth
Mummification
Embryonic Death
Infertility
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2
Q

How is PPV transmitted?

A

Oronasal in the non-immune sow followed by transplacental transmission.
Venereal transmission

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3
Q

How long does it take the virus to reach the fetus in the nonimmune sow?

A

15 days

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4
Q

What is a typical sign of transplacental infection?

A

Death at different stages of pregnancy because each fetus has a separate placenta. The virus spreads through the uterus to infect all remaining fetuses.

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5
Q

Where is the primary site of virus replication?

A

Mitotically active cells in fetal tissues

However, excessive endothelial cell damage may be reflected in damage to many organs.

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6
Q

What is the hallmark of PPV?

A

Increase in mummified fetuses after a normal gestation period.
Abortions are uncommon.

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7
Q

What are the results of early, mid, and late fetal infections?

A

< 30 days: Dies and resorbed.
30-70 days: Died and mummified
>70 days: Usually survive

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8
Q

What are the clinical signs of PPV in adults?

A

Inapparent or subclinical

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9
Q

What does it mean if a pig is immunotolerant to PPV?

A

They can shed the virus continuously or intermittently.

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10
Q

What are less common clinical symptoms of PPV?

A

Respiratory Tract Infections
Vesicular Disease
Systemic Neonatal Disease

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11
Q

Is serology useful in detection of PPV?

A

No because the virus is so widespread in swine and vaccination interferes

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12
Q

How is PPV diagnosed?

A

FA staining of frozen sections of fetal tissues
PCR for nucleic acid in fetus
ELISA

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13
Q

How long is passively acquired maternal antibody good for?

A

6 months

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14
Q

Unlike most parvoviruses, what does PPV not cause?

A

Persistent infection with petrological shedding of the virus

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15
Q

What is the best method of vaccination?

A

Vaccinate all susceptible breeding stock twice, 2 weeks apart, several weeks before breeding

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