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Flashcards in Pathology Exam 1 Material Deck (161)
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1

True or false: you will always see bile imbibition in a necropsy

False. It takes a while to occur, so you won't always see it

2

Is tympany a pre-mortem or post-mortem change?

Tympany is a pre-mortem change.

It can be differentiated from bloat by looking for esophageal blanching

3

Hypertrophic cardiomyopathy is common in which breed of cat?

Maine coon

4

An increase in the number of cells of an organ is called:

hyperplasia

5

A change in the phenotype in a differentiated cell is called:

Metaplasia

6

Metaplasia is most commonly seen in which type of cells?

Epithelial cells

7

Malignant tumor of epithelial cell origin: ____________

Carcinoma

8

A decreased # of RBCs in blood, blood volume, or Hb deficiency is called:

anemia

9

Cyanide toxicosis can occur when a cow eats plants with _________ acid

Cyanide toxicosis can occur when a cow eats plants with prussic acid.

Cow eats plants with prussic acid --> microbes produce free cyanide --> free cyanide is absorbed and reacts with Fe3+ (ferric iron) in cytochrome oxidase --> cellular respiration

10

Impaired blood flow to tissues is also called:

Ischemia

11

Copper storage disease is a genetic deletion of Murr 1 gene in what breed of dog?

Bedlington Terriers

12

Lack of tyronsinase causes ___________

albinism

13

True or False: You can use PAS as a stain for lipofuscin

True.

14

___________ is also known as the "wear and tear pigment"

lipofuscin

15

What does it mean for a disease to be multifactorial?

It has more than one cause

16

A list of diseases that could account for the evidence or lesions of the case is known as:

differential diagnosis

17

Negri bodies in nerves are pathognomonic for ________

rabies

18

Is liver mortis a pre- or post-mortem change? What about hypostatic congestion?

Post-mortem change!

(Livor mortis & hypostatic congestion are the same thing)

19

If there is a clot that is completely unattached to the vessel walls, is it a pre- or post-mortem clot?

post-mortem clot

20

Which will bloat more quickly: herbivores or carnivores?

herbivores.

Bloating results from post-mortem bacterial gas formation in the lumen of the GI tract. Herbivores have a higher presence of GI tract microbes

21

increased size of cells and their functions is called:

hypertrophy

22

Will we see hyperplasia in the heart? Why?

No.

Hyperplasia is an increase in the number of cells of an organ. Cardiomyocytes do not have the capacity to divide!!

23

Only tissue lined by ________ can undergo hyperplasia

epithelium

24

inadequate oxygenation of tissues is called:

hypoxia

25

__________ refers to the accumulation of triglycerides and other lipid metabolites (neutral fats and cholesterol) within the cytosol of parenchymal cells

lipidosis

26

Which stain(s) is/are used to confirm lipidosis?

Oil Red O; Sudan IV

27

Coagulative necrosis is commonly caused by _________ in all solid organs except the brain

ischemia

28

a localized area of coagulative necrosis is called:

an infarct

29

Which cattle breeds are most susceptible to necrosis of abdominal fat?

Jersey & Guernsey

30

Morphological diagnosis?

Multifocal, acute renal necrosis and hemorrhage

or

Multifocal, acute necrohemorrhagic nephritis