What is the brown pigment present in this fresh intestine from a dog?
T/F: Fibrin is typically associated with chronic processes
You don't see fibrin in chronic processes because by then it should already by phagocytosed. You will however see fibrous tissue
Acute inflammatory processes are partially characterized by the emigration of white blood cells to the sites of inflammation. Which type of cells make up most of these WBCs?
Would this image be more accurately described as acute or chronic?
Note the presence of fibrous tissue
Name the cytokines induced when PAMPs and TLRs bind:
IL-1, TNF-a, and Interferon (IFN)
*has been a test question*
Name the toll-like receptor (TLR) associated with LPS (Gram-negative):
Name the toll-like receptor (TLR) associated with lipotheicoic acids (Gram-positive):
Name the toll-like receptor (TLR) associated with lipoarabinomannon (Mycobacteria):
TLR2 and TLR4
When neutrophils cannot engulf a particle due to size, it will spew out contents in an attempt to neutralize it, then it is eaten by macrophages.
What is this process known as?
What is the 'main cell' in the acute inflammatory response?
Inflammatory sites rich in neutrophils are referred to as _________ and __________
Inflammatory sites rich in neutrophils are referred to as suppurative and purulent
Avian species do not have neutrophils. Instead, they have:
Which cell type do you expect to be more abundant in inflammatory diseases of immunologic, parasitic, or allergic origin?
Name the 7 major chemoattractants associated with eosinophils:
Name the etiology associated with the image.
Etiology: Habronema spp.
EDx: Habronemal dermatitis/coronitis
(balanoposthitis is inflammation of the foreskin and head of the penis)
T/F: lymphocytes and plasma cells are commonly seen in innate immune responses
lymphocytes and plasma cells are commonly seen in adaptive immune responses
Name the tachykinin responsible for inducing degranulation of mast cells, basophils, eosinophils and release of their histamine
Which complement product functions in opsonization?
Histamine is present in tissues, basophils, and platelets, but primarily in ____________
Which cytokines play the biggest role in hematopoiesis?
TNF and IL-1, the two major cytokines in acute inflammation, are produced primarily by:
What is the primary cytokine associated with fever?
The pathologic state characterized by weight loss and anorexia that accompanies some CHRONIC infections and neoplastic diseases is known as:
T/F: Chemokines are produced by all nucleated cells
If you see fibrin, you automatically know that the process is __________
(acute or chronic)
Inflammation of the lymph nodes is known as:
Inflammation of the lymphatic vessels is known as:
LPS from gram negative bacteria can stimulate the release of inflammatory mediators.
The receptor that recognizes LPS is:
TLR-4 is a pattern recognition receptor that recognize PAMPs such as LPS, lipotechoic acid, and lipoarabinominnon.
T/F: Fibrosis is a sign of acute inflammation.
Fibrin deposition may be seen in acute inflammation. Fibrosis is an indication of chronic inflammation