pathology of the pancreas Flashcards

(70 cards)

1
Q

the most common causes of acute pancreatitis is ___ tract disease and excessive ___ ____

A

Billiary
alcohol intake

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2
Q

____ ___ is acute inflammation of the pancreas

A

acute pancreatitis

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3
Q

with acute pancreatitis there is elevated
- blood and urine ______
- blood _____
- ___ count
- ______

A

amylase
lipase
WBC
bilirubin

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4
Q

in acute pancreatitis blood and urinary amylase are elevated within first ____ hours and stays elevated for __-___ hours

A

24
48-72

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5
Q

with acute pancreatitis blood lipase elevated within ___-___ hours and stays elevated ___-___ days

A

48-72 hrs
5-14 days

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6
Q

some signs and symptoms of ACUTE pancreatitis are
- severe ___ pain which radiates to back ( after large meal or alcoholic Bev)
- nausea and vomiting
- ____
- abdominal ____
- fever
- _____
- history of gallstones and ____ abuse

A

epigastric
malaise
abdominal DISTENTION
jaundice
ALCOHOL abuse

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7
Q

on ultrasound ACUTE pancreatitis in the early stage may appear ____.
late stage shows an enlarged, ____echoic pancreas with possible pancreatic duct diation .
peripancreatic fluid collection with possible ____.
doppler shows ___ blood flow .
the gallbladder wall may be _____

A

normal
HYPOechoic
ascites
increased
thickened

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8
Q

there are 2 forms of ACUTE pancreatitis ____ form and ____ form

A

edematous
necrotizing

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9
Q

the most common form on pancreatitis is ____ form

A

edematous

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10
Q

some complications of ACUTE pancreatitis are
- ____ formation
- _____
- abscess
- _____
- duodenal _____

A

pseudocyst
phlegmon
hemorrhage
obstruction

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11
Q

pancreatic pseudocyst develops __-___ weeks onset of pancreatitis

A

4-6

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12
Q

the most common location for a pancreatic pseudocyst is the ___ sac anterior to the pancreas and ___ to the stomach.
The second most common location is in the anterior ___ space

A

lesser
posterior
pararenal

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13
Q

___ is used as a guidance modality in the approach to precutaneus drainage of pancreatic pseudocyst and abscess

A

ultrasound

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14
Q

for surgical or precutaneus intervention __ to ___ weeks is considered appropriate because by that time the walls of the pseudocyst are relatively well formed and the chances for spontaneous regression have diminished

A

five to six

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15
Q

pancreatic pseudocyst more common location is in the ___ ___

A

lesser sac

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16
Q

pancreatic pseudocyst second most common location is in the ___ ___ ___

A

anterior pararenal space

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17
Q

some complications with pancreatic pseudocyst are
- ____, infection and ____ rupture

A

bleeding
spontaneous

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18
Q

the most common complication of a pancreatic pseudocyst is ___ ___

A

spontaneous rupture

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19
Q

a spontaneous rupture clinical symptoms are sudden shock and ___, mortality rate is __% and pancreatic ____

A

peritonitis
50%
ascities

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20
Q

a complication of ACUTE pancreatitis is pancreatic ___ which is localized suppurative pus collecting in or around the gland

A

abscess

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21
Q

____ causes localized areas of diffused inflammatory edema or soft tissue.
its an inflammatory process that spreads along the fascial pathways

A

phlegmon

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22
Q

phlegmon may progress to ___ and suppuration. usually involves the __ sac, left anterior ___ space and transverse mesocolon.
occurs in 18-20% of patients with ___ ____

A

necrosis
lesser
pararenal
acute pancreatitis

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23
Q

phlegmon on ultrasound appears ___ texture with good through transmission

A

hypo echoic

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24
Q

____ pancreatitis is inflammatory reaction that spreads to the soft tissue surrounding the pancreas, along the fascial pathways producing edema and swelling

A

phlegmonous

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25
a pancreatic ___ is imaged with sonography with poorly defined hypoechic mass with smooth or irregular thick walls causing few internal echoes
abscess
26
_____ pancreatitis is caused by a sudden escape of pancreatic enzymes into the parenchyma causing focal areas of fat necrosis in and around the pancreas which leads to rupture of the vessels and ____
hemmorhagic hemorrhage
27
hemorrhagic pancreatitis is a rapid progression of ____ ____ with rupture of pancreatic ___ resulting in a ____
acute pancreatitis vessels hemorrhage
28
hemorrhagic pancreatitis on ultrasound appearance is varied , depending on the ___ of the hemorrhage ; ___ defined homogenous mass in the area of the pancreas may be seen , may appear ___ or ____
age well solid or cystic
29
____ ____ is an irreversible progressive destruction of pancreas due to repeated episodes of acute pancreatitis
CHRONIC pancreatitis
30
CHRONIC pancreatitis most common cause is ___ ___ associated with chronic ___ or ____ disease
alcohol abuse alcoholism biliary
31
CHRONIC pancreatitis increases risk of patient developing ____ ____
pancreatic cancer
32
with CHRONIC pancreatitis patients may also have ____ ( 20-40%) , a dilated ___ ___ ___ . or ___ of the splenic vein with extension into the ___ vein
pseudocyst common bile duct thrombosis portal
33
some signs and symptoms of CHRONIC pancreatitis is - constant ____ and ___ pain - _____ loss -_____ - _____ mellitus
epigastric and back weight steatorrhea diabetes
34
CHRONIC pancreatitis on ultrasound appears ____geneous, small echogenic ____ may be seen , ___ contours and ____ pancreatic duct
HETEROgeneous calcifications irregular dilated
35
36
Endocrine neoplasms is also known as ____ cell tumors
Islet
37
Exocrine neoplasms is also called ____ cell tumors
Acini
38
The three types of islet cell tumors are - ____ (B cell ) - _____ - ______ ( G cell)
Insulinoma Glucagonoma Gastrinoma
39
The most common islet cell tumor is _____ (60%) And the second most common is _____ (18%)
Insulinoma Gastrinoma
40
Insulinoma (B cell ) is usually ____ and secretes ____.
Benign Insulin
41
Glucagonoma is ___. High incidence of ___ .
Rare Malignancy
42
Gastrinoma (G-cell) is the second most __\ functioning islet cell tumor and produces ___ -___ syndrome
Common Zollinger Ellison
43
Gastrinoma is caused by non___ secreting pancreatic tumors , which secrete excessive amounts of ___
Insulin Gastrin
44
With Glucagonoma patients are ____ caused by increasing level of the glucagon hormone
Hyperglycemic
45
Insulinoma , Glucagonoma and Gastrinoma are usually found on the pancreas ___ and ____
Body Tail
46
The types of acini cell tumors are - ______ - _______ - _____/_____
Adenocarcinoma Serous cystadenoma Mucinous cystadenoma / cystadenocarcinoma
47
Adenocarcinomas are ___ tumors of pancreas ranked as ___ th leading cause of cancer related deaths in the US
Malignant 4
48
____ accounts for 90% of all pancreatic malignancies. It can produce ___ gallbladder which is dilated CBD and GB
Adenocarcinoma Courvoisier
49
With adenocarcinoma lab values show elevated - _______ - _______ -________ - _____ phosphate
Bilirubin Amylase Lipse Alkaline
50
____ is a rare neoplasm it can be serous or mucinous
Cystadenoma
51
With cystadenoma most are ____ but does have ____ potential this would be called _____
Benign Malignant Cystadenocarcinoma
52
SEROUS cystadenoma is a ___ tumor . It’s more common in ___
Benign Women
53
MUCINOUS cystadenoma or cystadenocarcinoma is a ___ tumor but can become ____ and is most common in ____
Benign Malignant Woman
54
SEROUS cystadenoma is commonly found in the pancreas ____. MUCINOUS cystadenoma is commonly found on pancreas ___/____
Head Body/ tail
55
____ _____ is an adenocarcinoma most common type
Pancreatic carcinoma
56
Pancreatic carcinoma involves ____ portions of pancreas
Exocrine
57
Pancreatic carcinoma accounts for more than 90% of all ____ pancreatic tumors
Malignant
58
Pancreatic carcinoma affect ____ people more that ____
Black White
59
Pancreatic carcinoma affects ____ more than ____
Males Females
60
Patients are at risk for pancreatic carcinoma with a diet high in ___ . Increase with ___. Family ____ correlation ____ pancreatitis . And with ____
Fats Smoking History CHRONIC Age
61
_____ ____ is the 4th most common cause of cancer related to breast and colon cancers
pancreatic carcinoma
62
lab values that relate to pancreatic carcinoma are elevated ______, _____, ______ and ______ phosphatase
bilirubin amylase lipase alkaline
63
the Courvoisier gallbladder sign is seen with ____ _____
pancreatic carcinoma
64
pancreatic carcinoma is most common in the pancreatic _____, it appears as a ____ echoic mass and _____ defined. its usually greater than __cm.
head HYPOechoic poorly 2cm
65
with pancreatic carcinoma on ultrasound you can see the dilated ___ ___ ( including intrahepatic ducts) through the ____. and division of ____ duct. Liver ____, ascites and regional _____
biliary tree CBD Pancreatic mets adenopathy
66
pancreatic carcinoma appears ____echoic with ____ boarder mass located on the ____ of the pancreas. Dilated ____
HYPOechoic irregular head CBD
67
_____ _____ is an inherited disorder of the exocrine glands causing viscous ( thick mucous) secretion and dysfunction of the pancreas exocrine function
Cystic fibrosis
68
with cystic fibrosis the pancreas becomes ____ and ___ replacement occurs
fibrotic fatty
69
cystic fibrosis can cause pancreatic duct ____
obstruction
70
with cystic fibrosis there is pancreas ____ with increased ____ caused by fat replacement of the pancreatic tissue
atrophy echogenecity