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Flashcards in Pathology of Viral Infections Deck (60)
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1

[Incubation Period] Dengue

3-14 days (ave 4-7)

2

[Diagnosis] Dengue

isolating the virus, detecting viral antigen or RNA in serum or tissues, or detecting specific antibodies in the patient's serum

3

[Symptoms] Dengue

acute onset of fever accompanied by frontal headache,
retro-orbital pain, body aches, nausea and vomiting,
joint pains, weakness, and rash.

4

What disease is caused by Rhinovirus?

Respiratory Diseases

5

[Incubation Period] Rhinovirus

1-2 Days

6

[Diagnosis] Rhinovirus infection

culture from washings or nasal
secretions

7

[Symptoms] Rhinovirus infection

rhinorrhea, sneezing, and nasal congestion,may have sore throat,

but mild or absent constitutional s/s like body malaise and headache; fever unusual

8

[Clinical Management] Rhinovirus infection

not necessary, since self-limited

9

[Incubation Period]
Respiratory Syncytial Virus Pneumovirus

4-6 days

10

[Diagnosis]Respiratory Syncytial Virus Pneumovirus

isolation of RSV from respiratory secretions,
including sputum, throat swab, and nasopharyngeal
washes

11

[Symptoms] Respiratory Syncytial Virus Pneumovirus

begins with rhinorrhea, low grade fever, cough and
wheezing, mild systemic symptoms

12

[Management] Respiratory Syncytial Virus Pneumovirus

respiratory therapy, including hydration, suctioning of
secretions, administration of humidified O2, antibronchospastic agents, even ventilatory assistance

13

[Symptoms] Mumps

Parotitis, orchitis, encephalitis

14

[Viral Agent] Measles

Rubeola virus

15

[Diagnosis] Measles

mononuclear cell infiltration and multinucleate giant cells.xlymphoid hyperplasia prominent in cervical and
mesenteric lymph nodes, spleen appendix

16

[Disease] rash – blotchy, reddish-brown – produced by dilatedskin vessels, edema, and a moderate, nonspecific, mononuclear perivascular infiltrate (a vasculitis of small blood vessels)

Measles

17

[Prodromal Period] Rabies

2-10 days

18

[Disease] transient viremia and fever, spinal or brainstem bulbar

Polio

19

[Disease] characterized by rash, arthralgias, and transient interruption in erythrocyte production

Parvovirus B19

20

[Disease] general malaise, chills, fever, headache S/s of CNS dysfunction like anxiety, agitation, paralysis, episodes of delirium, “furious” and “dumb”

Rabies

21

[Clinical Management] Polio

anti-virus antibodies control the disease in most cases, vaccine

22

[Incubation period] Parvovirus

4-14 days

23

[Incubation Period] Small Pox

12-14 days

24

[Incubation Period] Hand, Foot and Mouth Disease

4-7 days

25

Dengue Virus
a. Flaviviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

26

HPV
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

D

27

Rhinovirus
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

28

Coxsackie Virus
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

29

Rabies
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

C

30

Mumps Virus
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

E

31

Respiratory Syncitial Virus/Pneumovirus
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

E

32

[Duration]
Dengue acute febrile period

2-10 days; negative serology; still mounting antibody response

33

Platelet count in DHF

100,000/mm3, note normal: 150,000/mm3

34

[Identify]
Small, non-enveloped ssRNA, acid labile and grows best at 33-34degC

Rhinovirus

35

Which antibody is protective against Respiratory syncitial virus?

Nasal IgA neutralizing antibody

36

ssRNA enveloped Paramyxiviridae with large surface glycoprotein with both hemagglutinin and neuraminidase activity

Mumps virus

37

[Viral pathogen]
German measles

Rubella

38

[Viral pathogen]
Chicken pox, shingles

Varicella, varicella-zoster

39

Rubella
a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

E

40

Protection against Rubella is via
a. cell mediated immunity
b. antibody mediated immunity

B

41

ulcerated mucosal lesions in the oral cavity near the opening of the stensen's duct

Koplik spots

42

Measles giant cells a.k.a

Warthin-Finkeldey cells

43

Round eosinophilic cytoplasmic
inclusions measuring 1-7 μm are pathognomonic of rabies

negri bodies

44

What is the preferential site for negri body formation

hippocampal neurons

45

Polio __ attenuated vaccine can in some cases
revert back to wild type (most pathogenic)

Polio 3 attenuated vaccine can in some cases
revert back to wild type (most pathogenic)

46

Which Polio strain is most virulent?

Polio1

47

killed, formalin-fixed polio vaccine
a. Sabin
b. Salk

B

48

live, attnuated polio vaccine
a. Sabin
b. Salk

A

49

which polio vaccine is less immunogenic?
a. Sabin
b. Salk

B

50

Neuronophagia is a typical manifestation of
a. rabies
b. polio
c. Herpes
d. Chicken pox

B

51

The ff are sexually transmitted except
a. HPV 16, 18
b. Molluscum contangiosum
c. Herpes
d. HIV
e. AOTA
F. NOTA

F

52

[Viral pathogen]
Infectious mononucleosis

Epstein Barr Virus

53

[Viral Pathogen]
Kaposi Sarcoma

Herpes Simplex 8

54

[Disease that it causes]
HPV Types 6,10, 11, 40-45

anogenital warts/ condyloma acuminata

55

[Disease that it causes]
HPV Types 16, 18, 31

squamous cell dysplacias and squamous cell carcinomas of the female genital tract;
16,18 most common
16 most common in the Philippines

56

Cytopathic effect of HPV infected cells;when squamous cells become large with shrunken nuclei enveloped in large cytoplasmic vacuoles

Koilocytosis

57

verrucae vulgares a.k.a

common warts

58

verrucae planae a.k.a

flat warts

59

condyloma acuminata a.k.a

anogenital warts

60

papular lesions located on the folds of moist intertriginous areas that coalesce to form flat, wartlike lesions, especially around the genitalia and anuslesions associated with secondary syphilis

condyloma lata