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Flashcards in Pathoma Deck (3)
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1
Q

Rituximab

A

anti-CD20 antibody that is used to treat sypmtomatic patients with follicular lymphoma

2
Q

What translocation is associated with follicular lymphoma?

A

t(14;18)

translocates Bcl-2 on chromosome 18 with the gene for the immunoglobulin heavy chain on chromosome 14

3
Q

What is a lymphoma?

A

neoplastic proliferation of lymphoid cells that forms a mass (the mass can arise in a lymph node, or be extra-nodal).