PBL 1

Question 1

Where does the demyelination occur in MS?

Answer 1

CNS, not PNS

-The myelin produced by oligodendrocytes is different than in PNS so the immune cells only target CNS

Question 2

How do you read an MS MRI?

Answer 2

MS - white spots are lesions
Bone = white
Air = black
Fluid = dark gray

Question 3

Prednisone

Answer 3

Given to reconstitute the BBB & reduce immune response 
-Same class and function as dexamethazone

Question 4

What questions do you ask when trying to diagnose MS?

Answer 4

• Fatigue
• Tingling, pain or numbness
• Problems with balance and walking
• Changes in vision
• Depression/emotional changes
• Impaired thinking/understanding
• Poor muscle coordination