PCOS LAB (4-6) Flashcards

1
Q

is the outer covering of the body and is the
largest organ of the
integumentary system.

A

SKIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

found on the palms and
soles of the feet, lacks hair follicles and sebaceous glands but has a very thick epidermis and encapsulated sense
organs in the dermis.

A

Glabrous skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

hair follicles and
sebaceous glands are both present, but there are no encapsulated sensory
organs.

A

Hairy skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

has large sebaceous glands associated with fine vellus hairs, contrasting sharply with the scalp, which contains large hair follicles.

A

Facial Skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Functions of the Skin (5)

A
  1. Protection
  2. Vitamin D production
  3. Sensation
  4. Excretion
  5. Body temperature regulation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

an auricular structure, made up of many layers of cells.

A

epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The special structure of the epidermis is
classified as ________ and is typical of vertebrate animals.

A

stratified squamous epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

It is responsible for producing the main barrier known as the horny layer or stratum corneum,

A

Epidermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

forms the outermost part of the
epidermis.

A

Horny layer or Stratum corneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The horny layer is made up of water-resistant
dead cells, called ______ , which are
segmented together with a complex lipid material.

A

corneocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Lower living layers of the Epidermis (3)

A

-germinative or basal layer;
-stratum spinosum or prickle cell layer
-stratum granulosum or granular layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Germinative Layer

A

Basal Layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

stratum spinosum

A

prickle cell layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

stratum granulosum

A

granular layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

characterized by the presence of distinctive keratohyalin granules

A

stratum granulosum or granular layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

functions as a supporting frame to the
epidermis, supplying it with nutrients via the blood
capillaries_ It also supports the sensory nervous
system, secretory glands and hair follicles.

A

Dermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Unlike the epidermis, which is a cellular structure, the underlying dermis consists of ________

A

connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

forms the major constituent of the fibrous protein which gives the skin its tensile strength.

A

Collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

The dermal ___ substance consists of salt, water and glycosaminoglycans.

A

Ground substance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Ground Substance | The latter form complexes with protein molecules known as _____

A

proteoglycans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

The _______, which are the second major cell type in the dermis, can be found close to the small blood vessels.

A

Mast cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Composition of Dermis (5)

A
  1. Collagen and elastin
  2. Ground substance
  3. Mast cells.
  4. Sweat glands
  5. Sensory skin receptors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Below the epidermis is a layer of fatty or adipose tissue called the

A

Hypodermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

The cells in this layer (Hypodermis) synthesize and store fat as an energy reserve. This is to help insulate the body from low
external temperatures and to act as a
____ against trauma.

A

Buffer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
On a more familiar note, the ______ provides the body with its contours, whether they are attractive curves or unwelcome bulges_
Hypodermis
26
are complex mixtures of chemical agents specially designed to make the external layers of the skin softer and more liable.
Moisturizers or emollients
27
Moisturizers or emollients increase the skin's hydration (water content) by reducing _______
evaporation
28
Part of the composition of commercial skin moisturizers. (5)
Naturally occurring skin lipids and sterols, as well as artificial or natural oils, humectants, emollients, lubricants,
29
usually are available as commercial products for cosmetic and therapeutic uses, but can also be made at home using common pharmacy ingredients.
Skin Lotion
30
are liquid suspensions or dispersions intended for external application; some consist of finely powdered, insoluble solids held in more or less permanent suspension by suspending agents or surface-active agents, or both; others are oil-in-water emulsions stabilized by surface-active agents
Skin Lotion
31
Types of Skin (5)
* Normal Skin * Dry Skin * Oily skin * Aging Skin * Sensitive Skin
32
can be used to prevent the skin from becoming too dry or oily, such as with light, non-greasy water-based ____.
Moisturizers
33
Such moisturizers often contain lightweight oils, such as _____
cetyl alcohol, or silicone-derived ingredients Eg- cyclomethicone.
34
For treating skin dryness, the most appropriate moisturizers are ________ that contain ingredients such as antioxidants, grape seed oil or dimethicone.
heavier, oil-based moisturizers
35
For very dry, cracked skin, ____________ are preferable, as they are more lasting than creams and are more effective in preventing water evaporation.
petrolatum-based products
36
For oily skin, ____________ that are specifically non-comedogenic are preferable, as there is less risk of comedone formation.
water-based moisturizers
37
* Appropriate moisturizers to keep aging skin soft and well hydrated are _________ that contain petrolatum as the base, along with antioxidants or alpha hydroxy acids against wrinkles
oil-based
38
On sensitive skin (which otherwise is susceptible to skin irritations, redness, itching or rashes), it is preferable to use moisturizers which contain _______ ingredients such as chamomile or aloe, and that minimize potential allergens such as fragrances or dyes, as well as irritants such as acids.
soothing
39
Factors influencing the lotion physical parameter (4)
* EMULSIFIER * DISPERSED PHASE * DISPERSION MEDIUM * PHASE VOLUME RATIO
40
INGREDIENTS OF MOISTURIZERS (3)
Humectant Emollient Occlusives
41
An ingredient in skin or hair products that draws moisture from the air to moisturize the skin and also promotes the retention of moisture in the skin
Humectant
42
Examples of Humectant (6)
* Glycerine * Propylene glycol * Sorbitol * Urea * Lactic acid * Hyaluronic Acid
43
-Supple, waxlike, lubricating, thickening agents that prevent water loss and have a softening and soothing effect on the skin, - A skin conditioning agent which helps maintain the smooth, soft pliable appearance of the skin. - Usually a grease or an oil that softens the skin and protects it from dryness.
Emollient
44
Examples of Emollient (6)
* Sunflower seed oil * Olive oil * Allantoin * Cocoa butter * Myristyl Myristate * Mineral oil
45
- substances that hold strongly to the surface of the skin, preventing access to the air and increasing absorption of cosmetic treatments. - Usually refers to an ____ shield or film that is spread onto the skin to slow or prevent moisture evaporation.
Occlusives
46
Occlusives (4)
Petrolatum Lanolin Candililla wax Dimethicone
47
is necessary to blend a water phase and oil phase into an emulsion, but consider the potential effect of the degree of ____on the product viscosity.
MIXING
48
A ________ of energy must be used to evenly mix the two phases and other additives.
MINIMUM
49
A _______ amount of mixing energy, however, can decrease the the particle size of the dispersed phase and hence affecting the emulsion viscosity.
HIGH
50
is generally less of a problem in cosmetic processing because the product or phase is usually fluid at elevated temperatures
Heating
51
is more commonly a problem with cosmetic emulsion because it generally increases product viscosity. ______ has a more important relationship to final product viscosity because of its effect on crystallite size and dispersion.
Cooling
52
In a typical operation, a finished lotion is cooled to room temperature in a compounding vessel, and then pumped through a filter to a storage tank where it is held for filling. The viscosity of lotion will be reduced by this step. Then the product may be pumped to the filling line. The product usually has a chance to build a network of bonds. A portion of these bonds, if broken, are sometimes permanently destroyed.
SHEARING
53
________or the reduction of particles to a small and uniform size and their even distribution in a medium, is related to shearing in that frequently used to create the particle breakdown.
HOMOGENIZING
54
The cosmetic industry usually resorts to for dispersing solids and insoluble liquids in a liquid phase and reducing the dispersed particles to a minimum size.
HOMOGENIZATION
55
Soft, smooth skin, with healthy appearance
Normal (Eudermic) Skin
56
Fine texture, flaky, and/or have poor elasticity
Dry Skin
57
Wrinkles and saggy skin
Aging skin
58
Shiny with enlarged pores
Oily skin
59
Broken capillaries, fine textured, dry skin
Sensitive Skin
60
Excessively oily w/ blemishes
Blemish Skin
61
Body Wash Criteria (4):
1. must exhibit good cleaning properties, 2. must exhibit good lathering characteristics, 3. must be mild to the skin (not cause drying or irritation) and 4. preferably should even provide a conditioning benefit to the skin.
62
_____ is a cleanser used since antiquity, and it remains a popular cleanser despite much negative press and the introduction of syndets.
Soap
63
SYN + DET
Synthetic Detergents
64
Body wash compositions that attempt to provide skin-conditioning benefits are known. Many of these compositions are aqueous systems comprising emulsified conditioning oil or other similar materials in combination with a lathering ___________
Surfactant
65
For patients who prefer a bar form, _____ cleansing bars provide good cleansing and are usually well- tolerated. Those who prefer a liquid cleanser form can benefit from using one of the newer body wash technologies, such as a product that will deposit petrolatum on the skin during use
SYNDET
66
______also presents a cleansing challenge. The skin undergoes many changes with age, some of which can impact the response to personal cleansing products
Aged skin
67
Cleanser choice can impact the elderly in a a number of ways. The natural decrease in _________ lipids and increased dryness can predispose aged skin to the drying effects of cleansers.
stratum corneum
68
the body wash can be separated by a separation means (6):
— centrifugation — ultracentrifugation — pipetting — filtering — washing — dilution
69
Lather volume of a mild body wash composition, a surfactant component or a structured domain of a mild body wash composition, is measured using a ________
graduated cylinder and rotating apparatus
70
The _______ is used to determine the percent of a structured domain or an opaque structured domain that is present in a mild body wash composition that comprises a Surfactant component.
Ultracentrifugation Method
71
has a firmer, gel like consistency,
Shower gel
72
____ is more like liquid soap.
Body Wash
73
Body Wash and Shower Gel differ slightly in ______
concentration
74
Negative aspects of bar soap (3)
— The potential to spread bacteria by using the same bar of soap. —A higher pH level which can dry out skin faster. — Can be hard to keep track of and hold when standing in the shower.
75
is the new kind on the block when it comes to soap, and with scores of brands and fragrances and names, it is as popular as ever. _____ comes in convenient containers that you can hang off your shower head or some other part of your shower.
Body wash
76
is one of the cons of using body wash over bar soap. It's easy to lose sight of just how much body wash you're dispensing onto your wash cloth, and much of the time the excess winds up down the drain.
Waste
77
______ like body wash also come with a higher price tag than bar soap most of the time.
Liquid Soaps
78
Chemical Content | Some of the ones to watch for include:
Triclosan Parabens BHA
79
Top 6 ingredients To Avoid Body Wash
SLES, SLS, Propylene Glycol, Cocamidopropyl betaine, Triclosan, DMDM hydantoin
80
Body Wash Ingredients (7)
* Coconut Oil — * Honey - * Liquid Castile Soap — * Vitamin E — * Eucalyptus Oil — * Sweet Orange Oil — * Lemon or Grapefruit Oil —
81
Top 6 Ing to Avoid | (very common foaming agent) skin irritant.
Sodium Laureth Sulfate aka SLES
82
Top 6 Ing to Avoid | (very common foaming agent)
Sodium Lauryl Sulfate aka SLS
83
Top 6 Ing to Avoid | (foaming agent)
Cocamidopropyl betaine
84
Top 6 Ing to Avoid | (antifreeze)
Glycol
85
Top 6 Ing to Avoid |(antibacterial and antifungal agent)
Triclosan
86
Top 6 Ing to Avoid | (antimicrobial)
DMDM hydantoin
87
the sticky substance formed by the attachment of bacteria coating that adheres to the pellicle
Plaque
88
is a thin acellular, glycoprotein.
Pellicle
89
Plaque, when not removed within 24 hours, forms a substance called ________
calculus or tartar.
90
Plaque calcifies when _______ precipitates from the saliva.
calcium salt
91
The Formation of _______ is attributed to the action of acids obtained from the oral bacterial metabolism of dietary carbohydrates.
Caries (tooth decay)
92
The build-up of plaque on the tooth surface usually aids the decay process by forming _______ on the teeth surface.
pockets or crevices
93
Brushing removes material from the tooth before it hardens into
Calculus
94
APPROACH TO CARIES PREVENTION (2)
Flossing Brushing
95
Products that enhance the removal of stains and plaque by the toothbrush.
Dentrifices
96
Non-sterile aqueous solution.
Mouthwash / Mouth spray
97
a product sprayed into the mouth for the purpose of temporarily eliminating or at least covering up bad breath
Breath Spray
98
Masking effect of Breath Spray (hours)
4-6 hours
99
Active Ingredients for Breath Spray (110)
-Calcium hydroxide -Magnesium hydroxide -Copper gluconate
100
Components of Mouthwash (8)
-Antibacterial agents -Alcohol -Humectants -Surfactants -Flavoring agents -Coloring agents -Fluorides -Sweetening agents
101
Antibacterial | % Cetyl Polyvinyl Chloride (CPC) - Chlorhexidine - Triclosan - Saline -
Cetyl Polyvinyl Chloride (CPC) - 0.05% Chlorhexidine - 0.12% Triclosan - 0.03% Saline - 0.9%
102
Present in the range of 10-20% -enhances the flavour, provides sharpness to the taste, aids in masking. -unpleasant taste of active ingredients, functions as a solubilizing agent for some flavoring agents.
Alcohols
103
Breath Spray | Alcohols act as a "____"
co-solvent
104
*Glycerin & sorbitol *5% to 20% of the mouthwash. *these agents increases the viscosity of the preparation & enhances the sweetness of the product.
Humectants
105
They aid in the solublization of flavors & in the removal of debris by providing foaming action. Poloxamer 407 & 338, Polysorbate 80.
Surfactants
106
Can be carried out against suitabl oral micro-organisms in a suitable liquid media or agar media against a control and determining their effectiveness against the growth.
In-vitro antiseptic activity
107
Done by collecting representative bacterial samples, before and after the use of mouthwash, and culturing and counting colonies on agar plate.
In-vivo antiseptic activity
108
Using chemical analysis. surlace tension effects. Level - Gas chromatograph. Fair-wells osmoscope etc.
Deodorizing effect
109
Accelerated stability study.
Stability Study
110
effect on dental caries, cleaning, astringent, oral soft tissues.
Other special test - Clinical trials