Pediatrics CIS

Question 1

first and most obvious sign of early puberty

Answer 1

thelarche

-breast tissue

Question 2

adrenarche

Answer 2

pubic and axillary hair

before, at about same time, well after appearance of breast tissue

Question 3

african american girls

Answer 3

begin puberty earlier than white girls

Question 4

puberty of male genital

Answer 4

testicular volume 4mL or more

with prader orchidometer beads

Question 5

breast bud stage

Answer 5

stage 2 tanner

Question 6

enlargement of scrotum and testes

Answer 6

stage 2 tanner

Question 7

precocious puberty

Answer 7

before

• age 8 girls
• age 9 boys

Question 8

evaluation of precocious puberty

Answer 8

bone age

adopted children - may be inaccurate DOB

Question 9

premature pubarche and thelarche

Answer 9

benign normal variant conditions

premature thelarche - girls <7-8 years

Question 10

central precocious puberty causes

Answer 10

hypothalamic hamartoma
-most common cause

or other tumors

Question 11

breast enlargement

Answer 11

first and most obvious sign of early puberty

Question 12

earliest sign of central precocious puberty in boys

Answer 12

enlargement of testes

> 4mL

Question 13

androgenic effects

Answer 13

acne
hirsutism
increased muscle mass
ciltoromegaly (females)

Question 14

boys younger than 9 years

Answer 14

incidence of CNS findings much higher than girls

-MRI part of evaluation

Question 15

tx central precocious puberty

Answer 15

GnRH analog or agonist

leuprolide

increases final adult height

Question 16

triad of precocious puberty, developmental delay, seizures

Answer 16

hypothalamic hamartoma