Periodontal Immunology

Question 1

Gingivitis ?

Answer 1

acute inflammation
normal physiological response to infection or injury

Question 2

Periodontitis ?

Answer 2

chronic inflammation
pathological inflammatory response associated with tissue destruction

Question 3

What microbial complexes are found in sub-gingival plaque?

Answer 3

• porphyromonas gingivalis
• treponema denticola
• tannerella forsythia

Question 4

Can periodontitis occur in the absence of bacteria?

Answer 4

No

Question 5

Virulence factors of P. gingivalis?

Answer 5

• gingipains - proteases with broad specificity
• asaccharolytic - nutrients from breakdown of proteins and peptides
• drives dysbiosis (in susceptible hosts)

Question 6

What can the aetiology of periodontitis be associated with:

Answer 6

= accumulated plaque bacteria
= presence of periodontal pathogens
= polymicrobial dysbiosis
= in susceptible hosts
= host- pathogen interactions determine susceptibility