Perseris

Question 1

Generic

Answer 1

Risperidone

Question 2

Manufacturer

Answer 2

Indivior

Question 3

Dosage

Answer 3

90mg and 120mg

Question 4

How supplied

Answer 4

One pouch with risperidone powder
One pouch with delivery system syringe and desiccant
One 18 gauge 5/8th needle

Question 5

Stay state

Answer 5

After first dose (1 month)

Question 6

Indication

Answer 6

Treatment of schizophrenia in adults

Question 7

Study

Answer 7

1 8 week trial, every 4 weeks vs. placebo. PANSS total score

Question 8

Loading dose

Answer 8

N/A

Question 9

Maintenance

Answer 9

Maintenance 90 or 120 dose mg

Question 10

How often

Answer 10

Once monthly

Question 11

Administration

Answer 11

Sub-Q in abdomen or back of upper arm

Question 12

Adverse events

Answer 12

Increased weight, sedation/somnolence, muscoskeletal pain

Question 13

Special population

Answer 13

Pregnancy: EPS and withdrawals symptoms in neonates with third trimester exposure
Renal and hepatic impatient: titrate on oral up to our less than 3mg before initiating at 90mg

Question 14

Drug interactions

Answer 14

Carbamazepine and other 3YP3A4 inducers decrease plasma concentrations of riperidone
Fluoxetine, paroxetine, and other strong CYP2D6 inhibitors increase risperidone concentrations

Question 15

Storage

Answer 15

Refrigerate 36-46F. Allow come to room temperature. 68F-77F more than 15 minutes before mixing
Can be stored unopened at room temperature for 30 days. After removal from refrigeration, use within 30 days