Pharma Halo-halo 6 Flashcards

1
Q

oxybutinin

A

M3 antagonist

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2
Q

viagra MOA

A

PDE5 inhibitor

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3
Q

amifostine

A

rescue drug for cisplatin

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4
Q

leucovorin

A

rescue drug for methotrexate

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5
Q

MESNA

A

rescue drug for cyclophophamide

2-mercaptoethane sulfonate Na

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6
Q

rescue drug for doxorubicin

A

dexrazoxane

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7
Q

solve:

-1 = log (A/HA)

A
10^-1 = A/HA
1/10 = A/HA
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8
Q

Brothers of curare

A

gallamine, -curonium

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9
Q

brother of hexamethonium

A

trimetaphan

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10
Q

brother of nicotine

A

varenicline

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11
Q

MOA of betanechol

A

nonselective muscarinic agonits

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12
Q

brother of betanechol

A

pilocarpine

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13
Q

brother of oxybutinin

A

darifenacin

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14
Q

Short acting anticholinergics

A

ipratropium

oxitropium

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15
Q

LAMA

A

tiotropium

limeclidinium

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16
Q

nonspecific PDE inhibior

A

theophylline

-can be used as antidote for betablocker overdose

17
Q

PDE5 inhibitor

A

sildenafil

18
Q

PDE4 inhibitor

A

ROFLUMILAST

-severe COPD

19
Q

PDE3 inhibitors

A

Milrinone
Amrinone
Enoximone
-ACUTE DECOMPENSATED heart failure

Cilostazole
dipyridamole
-claudication
-antiplatelet
-s/e: headache (vasodilator)
20
Q

drug interactions of omeprazole

A

DIGOXIN
-increased gastric absorption

KETOKONAZOLE
-decreased gastric absorption

PHENYTOIN
WARFARIN
DIAZEPAM
CARBAMAZEPINE
-decreased metab by cyp

CLOPIDOGREL
-dec activatiotn by CYP2C19

METHOTREXATE
-blocks active renal secretion