Pharmacodynamics In Aesthetics Flashcards
(12 cards)
What is the pharmacodynamic action of botulinum toxin?
Inhibits acetylcholine release at the neuromuscular junction, preventing muscle contraction and reducing wrinkles.
Why is muscle anatomy important in aesthetic prescribing?
To accurately target injection sites and avoid complications like asymmetry or ptosis.
List two common adverse effects of dermal fillers and their causes.
Bruising (capillary injury) and vascular occlusion (injection into/near a vessel causing ischemia).
What is hyaluronidase used for in aesthetics?
To dissolve hyaluronic acid fillers in cases of complications or unsatisfactory results.
How do topical anaesthetics work pharmacodynamically?
They block sodium channels in nerve endings to inhibit pain transmission.
What is the mechanism of action of lidocaine?
Blocks sodium ion channels, preventing nerve signal transmission.
How should you respond to skin blanching and pain after filler injection?
Stop treatment and administer hyaluronidase to reverse potential vascular occlusion.
What is the likely complication of botulinum toxin treatment for glabellar lines?
Ptosis due to diffusion of botulinum toxin to the levator palpebrae muscle, inhibiting acetylcholine and causing muscle paralysis.
What is the diagnosis for immediate blanching and pain after lip filler injection?
Vascular occlusion.
Administer hyaluronidase to break down the hyaluronic acid filler and restore blood flow.
What could explain minimal improvement in forehead lines after botulinum toxin injections?
Insufficient dose, incorrect injection site, or antibody resistance. The drug may not effectively block acetylcholine at the neuromuscular junction.
What is the pharmacodynamic explanation for dizziness and metallic taste after topical lidocaine?
Systemic absorption of lidocaine causing CNS toxicity due to sodium channel blockade in the brain.
What pharmacodynamic considerations are relevant for botulinum toxin safety in patients with autoimmune disease?
Immune response may neutralize the botulinum toxin, reducing efficacy. Careful risk-benefit analysis is needed.
