Pharmacology

Question 1

Route of administration of UFH prophylaxis?

Answer 1

Subcutaneous

Question 2

Route of administration of UFH?

Answer 2

IV

Question 3

Route of administration of LMW Heparin?

Answer 3

Subcutaneous

Question 4

What could happen if heparin is given IM?

Answer 4

Hematoma

Question 5

When is LMWH monitored?

Answer 5

Obesity
Pregnancy
Renal insufficiency

Question 6

How is LMWH monitored ?

Answer 6

Anti Xa

Question 7

What allergies should be checked before giving heparin?

Answer 7

Cow & pigs

Question 8

Which surgery is heparin contraindicated in ?

Answer 8

Lumber puncture

Question 9

What is the half life of fondaparinux ?

Answer 9

15 hours

Question 10

How often should fondaparinux taken?

Answer 10

Once daily

Question 11

What is fondaparinux indicated for ?

Answer 11

Venous thromboembolism

Question 12

Univalent vs Bivalent direct thrombin inhibitors

Answer 12

Univalent: reversible & 1 site
Bivalent: irreversible & 2 sites

Question 13

What do we give a patient with a history of HIT?

Answer 13

Argatroban

Question 14

Route of administration of argatroban?

Answer 14

IV

Question 15

Route of administration of dibagtron?

Answer 15

Oral

Question 16

What is bivalirudin indicated for ?

Answer 16

Percutaneous coronary angioplasty

Question 17

What is dibagatron indicated for?

Answer 17

Prophylaxis from venous thromboembolism in patients who underwent hip / knee replacement

Question 18

What is heparin’s antidote?

Answer 18

Protamine

Question 19

What is dibagatron antidote?

Answer 19

Idarucizumab

Question 20

Route of administration of rivaroxiban?

Answer 20

Oral

Question 21

What anticoagulant do we give patients with nonvalvular atrial fibrillation to prevent stroke?

Answer 21

Rivaroxaban / Apixaban

Question 22

What anticoagulant do we give patients after knee/hip replacement to prevent venous thromboembolism?

Answer 22

Dibagatron / Rivaroxaban

Question 23

What is the antidote for rivaroxaban?

Answer 23

andexanet alpha

Question 24

What is the half life of warfarin?

Answer 24

36 hours

Question 25

Why is warfarin contraindicated in hypothyroidism?

Answer 25

Slower turnover rate of clotting factors

Question 26

What is cangrelor indicated for?

Answer 26

Coronary interventions

Question 27

What is the administration route of cangrelor?

Answer 27

IV

Question 28

What do we use for prophylaxis from thromboemboli for patients with prosthetic heart valves?

Answer 28

Warfarin + dipyridamol

Question 29

What can be used for percutaneous coronary intervention?

Answer 29

Bivalirudin or Abciximab

Question 30

What is the route of administration of GPIIb/IIIa inhibitors?

Answer 30

Parenteral

Question 31

What can we use to prevent cerebrovascular ischemia ?

Answer 31

Aspirin + dipyridamol

Question 32

What can we use for peripheral arterial disease?

Answer 32

Cilostazol / Vorapaxor

Question 33

What is the antidote for fibrinolytic drugs?

Answer 33

Aminocaproic acid

Question 34

What species is mycophenolate isolated from?

Answer 34

Penicillium glaucus

Question 35

Anticoagulant with longest half life?

Answer 35

Vorapaxor

Question 36

What anticoagulant do we use for acute cornoary syndrome

Answer 36

Ticagrelor + Aspirin Or GP IIb/IIIa inhibitors