Pharmacology 2 Flashcards by Rommel Bautista

Phenolpthalin and castor oil are

Stimulant laxatives or
Intestinal irritants

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Metamucil, psyllium husk, bran and dietary fibers are

BULK LAXATIVES

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Mg citrate and Na biphosphate are which type of laxative

OSMOTIC

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Na docusate is which type of laxative

SURFACE TENSION (softener)

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Dioctyl Na sulfosuccinate is also known as

DOCUSATE

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In laxative do not give ____ with mineral oil

COLACE

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Ca polycarbophyl is used in tx of

CONSTIPATION

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Glucocorticoid with highest potency

DEXAMETHASONE

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Glucocorticoid release is controlled by

HYPOTHALAMUS

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Prednisolone
Methylpred
Dexameth
Betamethasones

Are examples of

GLUCOCORTICOIDS

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Metoclopramide ADR that requires monitoring

TARDIVE DYSKINESIA

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Pencillin loses it’s activity by which reaction

HYDROLYSIS

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Drug that decreases PRELOAD

NITRATES

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Drugs that decreases AFTERLOAD

HYDRALAZINE
DIAZOXIDE

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Drug that decrease PRE/AFTERload

NA nitroprusside

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The drug with patient instructuction as:

Apply with non metalic applicator or tip to avoid erythema

Do not cover with occlusive dressing

Avoid prolonged sunlight/UV exposure

FLUOROURACIL

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Indicated for estrogen dependent neoplasm

TAMOXIFEN

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Drug with storage instruction:

Room temp do not refrigerate
Protect from light
Discard unused portion

CISPLATIN

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Cisplatin SE

NEPHPROTOXIC

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Tx of cisplatin toxicity

AMIFOSTINE

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Nitrogen mustard
Chlorambucil
Cyclophosphamide

Are which kind of cancer drugs?

ALKYLATING AGENTS

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MTX
6-Mercaptopurin (6-MP)
5-FU

Are which kind of cancer drugs?

Antimetabolites

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Prednisolone
Chlorambucil
Rho immunoglobulin
6-MP

Are useful ____ in chemotherapy

IMMUNOSUPPRESSANTS

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The max time before bone marrow depression (BMD) occur

NADIR

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Used in MTX toxicity

FOLIC/linic ACID

Is Na mercapto ethane sulfonate

MESNA

Alkylating agent which is a potent vesicant

MECHLOETHAMINE

Tx for extravasation/ unintentional leakage or escape of a fluid

THIOSULFATE COLD COMPRESS

A granulocyte stimulating factor which stimulate the production of neutrophils

FILGRASTIM

Used in the treatment of lung cancer, testicular cancer, and certain types of lymphomas and leukemias. It may be used alone or in combination.

ETOPUSIDE topoisomerase inhibitors. works by interfering with the DNA replication process of rapidly dividing cells, particularly cancer cells.

Anti cancer drug that is causing cardiac cumulative tocicity

DOXURUBICIN

Tx of breast/non small breast cancer

DOCETAXEL

Antibiotics use in cancer therapy

DACTINOMYCIN MITHROMYCIN

Cytarabine is not alkylating agent

Cytarabine

Cause total bone marrow depression

CYCLOPHOSPHAMIDE

Side effect of cyclophosphamide

HEMORRHAGIC CYSTITIS

Hemmorhagic cystitis cause by cyclophosphamide is treated with

MESNA

Bone marrow depression will lead to

AGRANULOCYTOSIS

Tx of cisplatin toxicity

AMIFOSTINE

Toxicity Caused by guanin e synthesis

6- thioguanine toxicity

5-FU causes which SE

MARKER BMD

Metastatic bone pain is treated by

FENTANYL PATCH

Used in methotrexate infusion to prevent toxicity

FOLIC ACID

Methotrexate toxicity treatment

LEUCOVORIN

shows higher activity because it differs to hydrocortisone in conformation in ring A

Prednisolone

Which drug has the following complications: Dessimination of local infection, infection susceptibility, masking symptoms of infection, osteoporosis

CORTICOSTEROIDS

Fluoridated corticosteroids are CI in

ROSACEA

Fludrocortisone is use in tx of

ADDISON's disease

Drug class that function as intermediate in metabolism, salt & water retention, muscle development and homeostasis

CORTICOSTEROIDS

Cortisol use can lead to rash on the face due to

TELANGIECTASIAS small, dilated blood vessels near the surface of the skin, commonly referred to as spider veins or broken blood vessels. SJS

Longterm use of corticosteroids will cause

OSTEOPENIA bone mineral density that is lower than normal but not low enough to be classified as osteoporosis

Relative potencies of different CORTICOSTEROIDS

Relative Potencies (Anti-inflammatory Effects): • Cortisol (hydrocortisone): 1 (as std) • Prednisone: 4-5 times • Methylprednisolone: 5-6 times • Dexamethasone: 25-30

Equivalent Doses (mg) of different CORTICOSTEROIDS

Equivalent Doses (mg): • Hydrocortisone: 20 mg • Prednisone: 5 mg • Methylprednisolone: 4 mg • Dexamethasone: 0.75 mg

Sodium-Retaining Potencies (Mineralocorticoid Activity) of different CORTICOSTEROIDS

Sodium-Retaining Potencies (Mineralocorticoid Activity): • Cortisol (hydrocortisone): Significant • Prednisone: Moderate • Methylprednisolone: Moderate • Dexamethasone: Minimal

Cough receptors are located in the

Brain stem- medulla

Ipecac expectorant dose

1ml

Use in depolymerization of mucous

BROMHEXINE

Acetyl cystein is given by

INHALATION

Tx of cystic fibrosis

Dornase NAC PANCREATIN

is a genetic disorder that primarily affects the respiratory and digestive systems. This leads to the production of thick and sticky mucus, which can clog the airways and ducts in various organs, such as the lungs and pancreas.

CYSTIC FIBROSIS

There is a change in ____ in cystic fibrosis. Sx

SWEAT

Diagnostic test for cystic fibrosis

FEV-1 Chloride in sweat

% occurence of different RNA

rRNA- 80% tRNA- 15% mRNA- 5%

NEVIRAPINE drug class

NNRTI

Kreb's cycle occurs in

MITOCHONDRIA (Respiration)

Storage in cell

GOLGI APARATUS

Contains cellular digestive enzyme

LYSOSOMES

Lipid synthesys in cell occurs in

SMOOTH ER

Protein synthesys in cell occurs in

ROUGH ER

RNA with specific amino acid attached

tRNA

Drug metabolism occur in which part of the cell

ER/ RIBOSOMES

Podophyllum resin is used in the tx of

WARTS

Otc drugs for Lice

PYRETHRINS PIPERONYL BUTOXIDE PTEROLLATUM DISTILLATE

Rx drugs for lice

CRETAMITON

Tx of rosacea

HYDROCORTISONE

Minocycline SE

NVD VESTIBULAR TOXICITY

Epidermis is also known as

KERATIN

Substance that remove comedones

Al(OH)3

T or f, impetigo can complicate to endocarditis

False

Tx of acne and psoriasis

TRAZOTENE

Toxic effects of clindamycin may be increased by

LOMOTIL

Loperamide in ulcerative colitis will produce

INTESTINAL PERFORATION

Related to miperidine, which stimulates the opiate center in GIT causing constipation

DIPHENOXYLATE

Citrate use in ORS

1. Alkalinizing Agent: 2. Enhance the flavor

MAOi can take red meat 🥩 but not

Wine Beer Chicken Liver Cheese

TCA with least anticholinergic SE

TRAZODON

Tranyl cypromine is a

MAOi ANTIDEPRESSANT

Lithium concentration is decreased by

THEOPHYLLINE

Onset of TCA requires

3-4 weeks

TCA should not be used together with

GUANTIDINE - alpha2 agonist

TCA is CI in which eye disease

GLAUCOMA also SEDATION ANTICHOLINERGIC effects TACHYCARDIA

TCA + MAOi

⬆️ action of MAOi

Antidepressant classes

TCA MAOi ALPHA blockers Tranylcypromine

Ampethamine Phenylephrine Ephedrine Tyramine + MAOi's

HYPERTENSIVE CRISIS

Affects neural amine reuptake mechanisms (Serotonin, NE)

TCA

Sertraline and fluoxetine belongs to which drug class

ANTIDEPRESSANTS- SSRI

SE of cyclobenzaprine is similar to

AMITRYPTILINE

Common SE of antidepressants

Antimuscarinic effects Postural hypotension Drowsiness

Venlafaxin specific SE

HTN

Patient on Li should not restrict which intake

SODIUM

Tranylcypromine should restict intake of

FOOD AND DRUGS

Pseudoephedrine should take precaution in taking

IPRONIAZID

A MAOi requiring dietary restriction

PROCARBAZINE

Inhibits reuptake of 5HT - increase conc SE: Heparic failure CI: Cisapride, TCA, MAOi, Terfinadine, astimazole

NEFAZODONE

Use of MAOi's

PSYCHOTROPIC ANTIDEPRESSANT ANTIEPILEPTIC

MAOi's SE:

HALLUCINATIONS TREMORS HYPERTHERMIA ANTICHOLINERGIC effects

Tranylcypromine Phenelzine Meclobimide Iproniazide Belongs to which antidepressant class

MAOi's

Used in bipolar disorder but causes SE: diabetes insipidus

LITHIUM

Lithium is used in bipolar disorder but causes SE: diabetes insipidus, hypothyroidism, convulsion(treated by?)

VASOPRESSIN

A MAOi antidepressant used with caution with TCA, Tyramine, levodopa, cathecolamines, pethidine, rawoulfia

IPRONIAZID ⬇️action of adrenergic blockers ⬆️action of oral hypoglycemics

Drugs for bipolar mood disturbances

LITHIUM CARBAMEZEPINE NA VALPROATE

Imipramine metabolized by demethhlation will yeild

DESIPRAMINE

SE of nortryptiline

CONSTIPATION

Impiramine + oral anticoagulant

⬆️ action of imipramine

Trazodone + MAOi

SEROTONIN SYNDROME

L-dopa + MAOi

HTN CRISIS

Methylphenidate + MAOi

⬆️ CNS STIMULATION

Anti hypertensive effect of guanethidine is inhibited by

TCA (Amitryptiline)

glaucoma, a condition characterized by increased intraocular pressure that can lead to optic nerve damage. These include: 1. Prostaglandin Analogs: They help reduce intraocular pressure by increasing the drainage of aqueous humor.

Examples include latanoprost and travoprost.

glaucoma, a condition characterized by increased intraocular pressure that can lead to optic nerve damage. These include: Beta-blockers: decrease the production of aqueous humor, thereby lowering intraocular pressure.

timolol and betaxolol

glaucoma, a condition characterized by increased intraocular pressure that can lead to optic nerve damage. These include: Alpha Agonists: reduces intraocular pressure by decreasing aqueous humor production and increasing its outflow.

Brimonidine

glaucoma, a condition characterized by increased intraocular pressure that can lead to optic nerve damage. These include: Carbonic Anhydrase Inhibitors: reduce intraocular pressure by inhibiting carbonic anhydrase, slowing down aqueous humor production.

Dorzolamide and brinzolamide

glaucoma, a condition characterized by increased intraocular pressure that can lead to optic nerve damage. These include: Rho Kinase Inhibitors: increases the outflow of aqueous humor.

Netarsudil

is a prodrug, meaning it gets converted to epinephrine (adrenaline) in the eye, which then helps reduce intraocular pressure by increasing the outflow of aqueous humor

Dipivefrin

Eyedrop not destroyed by heat (autoclave)

SULFACETAMIDE

Preservatives in eye drops

Cetrimide 0.005% Benzalkonium Cl 0.02% Phenyl Hg nitrate 0.02% Cholrocresol 0.1% Chlorhexidine 0.1% Na edetate 0.1% Chlorambutol 0.5%

Eyedrops storage condition of 2-8 •C

CORTISONE ED PHOSPHOLINE ED

Tx of allergic conjuctivitis

LOTEPREDNOL

Dose increment of latanoprost

30mg/day

Cyclopentolate is an eye drop medication commonly used as a mydriatic agent, meaning it dilates the pupil. Answer if asked to choose the odd among the group of miotic agents such as

morphine, codeine, epinephrine, pilocarpine, bromocriptine physostigmine/neostigmine pramipexole, timolol

Several drugs have been associated with visual disturbances as potential side effects.

HAPDE Hydroxychloroquine/Chloroquine Amiodarone- microdeposits, blur, photoS PDE-5 Inhibitors: color Digoxin: blurred or yellow-tinted Ethambutol: color

Contraindicate in NARROW angle glaucoma

ATROPINE HOMATROPINE EPINEPHRINE

Timolol afvantage over pilicarpine

LONGER DURATION NO VISUAL ACCOMODATION MINIMAL EFFECT- pupil size

Short acting mydriatic effect

ADRENALINE

Shelf life of Eyedrops

28 days

Duration of mydriasis by tropicamide

3-4 hours

Dose for ocusert pilo

Pilo 20- 20mcg/hr Pilo 40- 40mcg/hr Covering a week

Demographics of narrow angle glaucoma

10% of all glaucoma population

Miotic effect of this drug: Starts in 15-30mins Max reduction IOP in 2-4 hrs Duration 4-8 hrs For open angle galucoma, causing constriction of pupil and producing dimming night vision

PILOCARPINE

Eyedrops that is 3 hours shorter duration than atropine

CYCLOPHENTOLATE TROPICAMIDE

Used as replacement to pilocarpine intolerance/resistance

CARBACHOL

Eye drops for eye lid edema

GUANTHIDINE

syndrome is a chromosomal disorder that occurs in males and is characterized by the presence of one or more extra X chromosomes. Physical Features: physical characteristics such as tall stature, reduced muscle mass, gynecomastia (enlarged breasts), and a small testicular

Klinefelter syndrome

A uricosuric agent that increase excretion of uric acid

PROBENECID

Uric acid is a derivative of

PURINE

Tophus is also known as

GOUT

Probenecid should not be combined with these drugS

ASPIRIN INDOMETHACIN THIAZIDE

Phenylbutazone is used in

GOUT

Not to be taken with tea

ALLOPURINOL

Drug used it tx of gout that does not affect urate metabolism or secretion, it interferes inflammatory response to gout

COLCHICENE

Combination of Allopurinol (oxidation) with azathioprine and 6-MP will result to

⬆️concentration of azathioprine and 6-MP Not thioguanine- methylation

Allopurinol are safe to take with

Warfarin CPM

Inhibits xanthine oxidase

ALLOPURINOL Counselling: drink plenty of water

Decreases uricosuric effect of probenacid

ACETAMINOPHEN

an older term for what is now commonly referred to as Polycystic Ovary Syndrome (PCOS). Hyperandrogenism: Elevated levels of androgens (male hormones)

Stein-Leventhal syndrome

Skin contraceptive implant

LEVONORGESTREL

Antiemetic and apetite stimulant

DRONABINOL

Antiemetic that is CI with hypokalemic Hypomagnesemia Anti arrhythmias

DOLASETRON

Anti emetic/ anthelmintic

TARTAR emetic No longer used - toxicity

Vitamin CI with levodopa, parkinson, phenytoin

B6- PYRIDOXINE

A heat liable vitamin used in tx of BERIBERI (Wernicke-Korsakoff)

B1- Thiamine

Vitamin that is a precurson for NAD/FADH

Vit B2- Riboflavin

Also known as panthotenic acid

Vit B5

Niacin deficiency will result to

PELLAGRA

Cyanocobalamine deficiency

Pernicious Anemia

Impairs vitamin K absorption

MINERAL OIL

Phytonadione menadione is

P- Vit K1 M- Vit K2

Folic in pregnancy to prevent

SPINA BIFIDA

Fish liver oil contains

VIT a/d

Iron form least absorbed by intestines

FERRIC

Vitamin with lactone structure

VITAMIN C

Vitamine with steroid structure

VITAMIN D

Ascorbic acid with methenamine is used for

URINARY CYSTITIS

Probucol is

ANTIHYPERLIPIDEMIC

Most common SE of simvastatin

HEPATOTOXIC

Drug interaction simvastatin + warfarin

Inhibit warfarin metabolism BLEEDING

TXA2 cause

Platelet agregation

Primary response to antigen

T/B cells

T cells matures in

THYMUS GLAND

IMMUNOGLOBULIN • Role: Found in mucous membranes, saliva, tears, and other bodily fluids, helps prevent pathogens from entering the body through mucosal surfaces. It plays a key role in local immune defense.

1. IgA (Immunoglobulin A)

IMMUNOGLOBULIN • Role: Although its precise function is not fully understood, is primarily found on the surface of B cells, where it may be involved in the activation of these cells during the immune response.

IgD (Immunoglobulin D)

Immunoglobulin • Role: Associated with allergic reactions, binds to mast cells and basophils. Upon exposure to allergens, triggers the release of histamine and other chemicals, leading to allergic symptoms.

3. IgE (Immunoglobulin E):

IMMUNOGLOBULIN • Role: The most abundant antibody in the bloodstream, provides long-term immunity. It can cross the placenta, providing passive immunity to the fetus. is crucial for neutralizing toxins and enhancing phagocytosis.

IgG (Immunoglobulin G):

IMMUNOGLOBULIN • Role: Produced in the early stages of an immune response, is often the first antibody to appear after exposure to an antigen. It is effective at agglutination (clumping) of pathogens.

IgM (Immunoglobulin M)

Hypersensitivity TYPE • Mechanism: Involves IgE antibodies and mast cells or basophils. • Examples: Allergic reactions such as hay fever, asthma, anaphylaxis to bee stings, or certain foods.

1. Type I Hypersensitivity (Immediate Hypersensitivity):

Hypersensitivity TYPE • Mechanism: Involves antibodies (IgG or IgM) targeting cell surface antigens, leading to cell destruction. • Examples: Blood transfusion reactions, autoimmune hemolytic anemia, and certain drug reactions.

2. Type II Hypersensitivity (Cytotoxic Hypersensitivity):

Hypersensitivity TYPE • Mechanism: Involves immune complexes (antigen-antibody complexes) that deposit in tissues, causing inflammation and damage. • Examples: Systemic lupus erythematosus (SLE), rheumatoid arthritis, and certain forms of vasculitis.

3. Type III Hypersensitivity (Immune Complex-Mediated Hypersensitivity):

HYPERSENSITIVITY TYPE • Mechanism: Involves T cells (specifically, cytotoxic T cells or helper T cells) and does not involve antibodies. • Examples: Contact dermatitis (e.g., poison ivy), tuberculin skin test reactions, and some autoimmune diseases.

4. Type IV Hypersensitivity (Delayed-Type Hypersensitivity):

WBC • Function: Phagocytosis (engulfing and digesting pathogens). • Role: They are the most abundant white blood cells and play a key role in the early stages of the immune response.

Neutrophils

WBC • Types: T cells, B cells, and Natural Killer (NK) cells. • Function: Adaptive immune response, including antibody production (B cells) and cell-mediated immunity (T cells).

Lymphocytes

WBC • Function: Phagocytosis and antigen presentation. • Role: They can migrate into tissues and differentiate into macrophages, which are large phagocytic cells.

Monocytes

WBC • Function: Defense against parasites and involvement in allergic reactions. • Role: They release substances that help modulate the immune response, particularly in allergic conditions.

Eosinophils

WBC • Function: Release histamine and other substances involved in inflammation. • Role: They play a role in the inflammatory response and are associated with allergic reactions.

Basophils

Occurs after second exposure to antigen

Anaphylactic reaction

Drug related anaphylaxis occurs after

2 minutes of drug administration

Myeloid reconstitution after bone marrow transplant

SARGAMOSTIN

Acts on estrogen in bones and lipids

RALOXIFENE

Cretinism in childrens is cause by which deficiency

IODINE

Contrindicated in breast feeding

COMBINED ESTROGEN

Inhibits folicular development and ovulation

ORAL CONTRACEPTIVES

Symptom of hypothyroidism

MYXOEDEMA

Test for human gonadotropins

WARNER LAMBENT TEST

Used for INFERTILITY

MENOTROPIN

Derived from theophylline, used in tx of PMS

PAMAPROM

AntiHTN with the most Ca ch blocking activity

VERAPAMIL

Contraindicated with digoxin, Ca, dysopyramide

VERAPAMIL

Triamterin diuretic class

K sparing diuretic

Toxicity of thiazied is due to decrease in

BLOOD VOLUME

Thiazides decrease tolerance of

GLUCOSE

A diuretic that is related to hyperurecimia, gout induction

THIAZIDE

Metabolic effects of diuretics

Thiazides/ loop- ALKALOSIS K- sparing- ACIDOSIS

Electrolytes effect of diuretics

Thiazides: ⬇️Na, Cl, K, Mg; ⬆️ Ca Loop: ⬇️Na, Cl, K, Mg, Ca K-sparing: ⬇️ Na; ⬆️ K, Cl;

Diuretics that antagonizes insulin

THIAZIDES

Is added to methyldopa to relieve salt and water retention

THIAZIDES

The MOA of amiloride is similar to

TRIAMTERENE

Main source of pheripheral resistance

ARTERIOLES

Anti hypertensive of guantadine is inhibited by

AMITRYPTILINE

TCA and corticosteroids can cause

HTN

Starting dose of HCTZ

50mg

Site of action of spironolactone

DCT

Sensitivity to sunlight is caused by

Bendroflumethiazide

SE of Ca Ch blockers

CONSTIPATION AND EDEMA

SE of B blockers

HYPOGLYCEMIC EFFECT DEC HDL COLD EXTREMITIES BRONCHOSPAMS

SE of amlodipine/ ACEi

PERIPHERAL EDEMA PRURITUS

Safe diuretic with sulfonamide sensitivity

ETHACRYNIC AC SPIRONOLACTON

Pallor or cyanosis of the fingers or toes

REYNAUD's Disease

Tx of HTN crisis in hospital

DIAZOXIDE

Patients taking indapamide should take

K SUPPLEMEMENTS

Hydralazine causes tachycardia which is treated by

PROPRANOLOL - First pass effect metabolism

Diuretics: Increase renal PG

LOOP DIURETICS

Initial drug therapy in HTN

THIAZIDES

Decreases Anti HTN effects of B blockers

INDOMETHACIN

Indapamide pts should take ___ and avoid____

K SUPPLEMENTS ALCOHOL

Cough by ACEi should be treated with

GUAIFFENESIN

A vasoconstrictor that should be avoided in HTN

Carbenoxolone is a drug that has been used historically for its anti-inflammatory and anti-ulcer properties.

HTN crisis caused by thyramine+ MAOi is treated with

ALPHA BLOCKERS

Hydralazine causes a syndrome resembling

SLE

Hydralazine cause anginal attack due to

CORONARY STEAL PHENOMENON

AntiHTN of choice for pts with renal insuffeciency

HYDRALAZINE

HTN pts on amitriptyline develops depression and tx should shift to

TRAZODONE

Is taken in the morning with food or milk

HCTZ

Combination of proranolol + ___ is not recommended

VERAPAMIL

Causes first dose effect: hypotension+ syncope

PRAZOSIN Not used for initial treatment

A centrally acting alpha 2 agonist

GUANABENZ

Appropriate perindopril dose

4-8 mg 16mg max dose/day

Antihypertensive drug not to taken with tyramine rich food

PARGYLINE

Overdose of Na nitroprusside will cause

CNS poisoning

A vasodilator acting by direct muscolotropic and B agonistic activity

NYLIDRIN (Buphenin)

Decreases after load

HYDRALAZINE

Is a arterrular/ venular dilator to be given by slow IV INFUSION

NA nitroprusside

Is similar to chlorthalidone

METOLAZONE

Increases effects of all antihypertensives

METHYLDOPA

Furosemide Bumetanide Ethacryninc acid

LOOP CI with gout

Interacts with digoxin and lithium

HCTZ

Hypertensive of choice in depression

HCTZ HYDRALAZINE

HCTZ in combination of this drug will decrease edema

PROPRANOLOL

CI with guanthidine and methyldopa

HALOPERIDOL

Gunathidine Methyldopa Clonidine Causes

BRADYCARDIA

Hydralazine causes

REFLEX TACHYCARDIA

Guanthidine interacts withs

TCA

Guanthidine makes parasympathetic tone predominate thus cause

DIARRHEA

Venule dilator

NITROGLYCERINE (glyceryl trinitrate)

Diaxozide Minoxidil Hydralazine Dilates?

Arteries

Duration of action of (t1/2) Thiazide Chlorthiazide Chlorthalidone

Thiazide 15hrs Chlorthiazide 3hrs Chlorthalidone 50hrs

TCA, OC clonidine withdrawal Corticosteroids Causes ___ HTN

IATROGENIC HTN

PRAZOCIN NITROPRUSSIDE KCL Drugs that cannot be given by

IV BOLUS

HCTZ dose

0.5-1g

Dose of chlorthiazide

500-2000mg/day

Diaxozide is administered by

RAPID IV INJ

Hyperaldosteronemia is

COON's

Should not be taken in HTN, bec of salt and water retention

CODEIN INDOMETHACIN

Bumetanide SE

MYALGIA

Increase vascular permeability to release PG12 to relax smooth muscles

BRADYKININS

Bendrofluazide SE

PHOTOSENSITIVITY

Least lipid soluble B BLOCKER

ATENOLOL

Type of HTN that need immidiate medical attention

ARTERIAL HTN

AntiHTN that causes angina

HYDRALAZINE

Diuretic CI with amitryptiline

CHLORTHIAZIDE

Least reflex tachycardia among ACEi

AMLODIPINE

Methyldopa antagonizes

TCA

All ACEi are prodrugs except

CAPTOPRIL LISINOPRIL

Acetazalomide cause systemic

ACIDOSIS

CI in asthma, renal artery stenosis, anti HTN class

ACEi

ACEi SE

HYPERKALEMIA ⬆️ CREATININE

Pulse is taken on

RADIAL ARTERY

Lisinopril max dose

20mg

Cough medicine for chesty cough With history of HTN + hyperlipidemia

GUAIFENESIN

Drugs used in HTN/angina

CCB/ B blockers

Pharmacology 2 Flashcards

(288 cards)