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Flashcards in Pharmacology Deck (21):
1

BUZZER

Modafinil is a drug used to treat what disorder?

Narcolepsy

2

BONUS

What is the class of drug for Modafinil and what is its MOA?

Sympathomimetic and blocks reuptake of dopamine

3

BUZZER

Decreased intestinal motility, constriction of pupils, decreased salivation, HTN, and smooth muscle contraction are associated with stimulation of what receptor?

Alpha-1 receptors

4

BONUS

List 3/5 places that alpha-1 receptors are found?

1. Arterioles/Veins
2. Glands
3. Urinary tract smooth muscle
4. Eyes
5. Intestine

5

BUZZER

Decreased NE release, DEC secretion from beta islet cells of pancreas, and DEC sympathetic outflow from the brain are all effects of what class of medications?

Alpha-2 receptor agonists

6

BONUS

List 2 contraindications to Modafinil?

1. Bipolar disorder
2. CVD disease

7

BUZZER

Tachycardia, INC renin secretion, INC cardiac contractility, and INC cardiac output are all effects of what receptor?

Beta-1 receptors

8

BUZZER

Relaxation of the bronchioles/trachea and uterus as well as dilation of arterioles and veins are effects of what class of medication?

Beta-2 receptor agonists

9

BUZZER

Non-specific beta blockers and beta-1 blockers are both?

Beta antagonists

10

BUZZER

What receptors does Epinephrine binds to?

Alpha and Beta

11

BONUS

What is Epinephrine's effect on the metabolic system?

Glycogenolysis and Gluconeogenesis

12

BONUS

Give 3 clinical uses for Epinephrine?

1. Bronchodilation
2. Anaphylaxis
3. Keep anesthetic in surgical area longer via blood vessel dilation

13

BUZZER

What cholinesterase inhibitor is used to Tx Alzheimer's dementia?

Rivastigmine

14

BONUS

List 3 conditions that may be contraindications in the prescription of Rivastigmine?

1. Hx of seizures
2. Asthma/COPD
3. Cardiac conduction defects (i.e. Sick Sinus Syndrome, Bradyarrhythmias)

15

BUZZER

Atropine should NOT be used in what condition?

Acute closed angle glaucoma

16

BUZZER

What is the antidote to Cholinesterase inhibitor poisoning?

Atropine

17

BONUS

Tachycardia, Tremors, Insomnia, Urinary retention, and appetite suppression are side effects from what class of drug?

Also may include Arrhythmias, HTN, Palpitations, HA, Restlessness, Difficult/painful urination

Sympathomimetic

18

BUZZER

What substance is decreased in the body when given the parasympatholytic/muscarinic agonist Atropine?

Ach

19

BONUS

What is Epinephrine's effect on the Pulmonary system?

Bronchodilation from beta receptors
Vasoconstriction and DEC secretions from alpha receptors

20

BONUS

What is Epinephrine's effect on the Cardiac system?

INC heart rate & contractility

21

BONUS

What is Epinephrine's effect on the vascular system?

Low dose: dilates vessels
High dose: constrict vessels