Flashcards in Pharmacology Deck (21):
Modafinil is a drug used to treat what disorder?
What is the class of drug for Modafinil and what is its MOA?
Sympathomimetic and blocks reuptake of dopamine
Decreased intestinal motility, constriction of pupils, decreased salivation, HTN, and smooth muscle contraction are associated with stimulation of what receptor?
List 3/5 places that alpha-1 receptors are found?
3. Urinary tract smooth muscle
Decreased NE release, DEC secretion from beta islet cells of pancreas, and DEC sympathetic outflow from the brain are all effects of what class of medications?
Alpha-2 receptor agonists
List 2 contraindications to Modafinil?
1. Bipolar disorder
2. CVD disease
Tachycardia, INC renin secretion, INC cardiac contractility, and INC cardiac output are all effects of what receptor?
Relaxation of the bronchioles/trachea and uterus as well as dilation of arterioles and veins are effects of what class of medication?
Beta-2 receptor agonists
Non-specific beta blockers and beta-1 blockers are both?
What receptors does Epinephrine binds to?
Alpha and Beta
What is Epinephrine's effect on the metabolic system?
Glycogenolysis and Gluconeogenesis
Give 3 clinical uses for Epinephrine?
3. Keep anesthetic in surgical area longer via blood vessel dilation
What cholinesterase inhibitor is used to Tx Alzheimer's dementia?
List 3 conditions that may be contraindications in the prescription of Rivastigmine?
1. Hx of seizures
3. Cardiac conduction defects (i.e. Sick Sinus Syndrome, Bradyarrhythmias)
Atropine should NOT be used in what condition?
Acute closed angle glaucoma
What is the antidote to Cholinesterase inhibitor poisoning?
Tachycardia, Tremors, Insomnia, Urinary retention, and appetite suppression are side effects from what class of drug?
Also may include Arrhythmias, HTN, Palpitations, HA, Restlessness, Difficult/painful urination
What substance is decreased in the body when given the parasympatholytic/muscarinic agonist Atropine?
What is Epinephrine's effect on the Pulmonary system?
Bronchodilation from beta receptors
Vasoconstriction and DEC secretions from alpha receptors
What is Epinephrine's effect on the Cardiac system?
INC heart rate & contractility