PHARMACOLOGY Flashcards

1
Q

Antiemetic that is contraindicated in patients wih seizure

A

Meperidine

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2
Q

What group of anesthetic drug that are CI in patients wih Myasthenia Gravis

A

Neuromuscular Blockers

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3
Q

Active metabolite in Meperidine that causes Seizure

A

Normeperidine

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4
Q

DOC for Myasthenia Gravis

A

Neostigmine

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5
Q

C/I in porphyria

A

Barbiturates

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6
Q

Anticholinergic to be used in caution in patienta with BPH

A

Ipatropium bromide

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7
Q

Cholinergic drug that can be used in Post-Op urinary problems

A

Bethanecol

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8
Q

In these drugs, we avoid cheese, whine or tyramine containig foods bec it causes hypetensive crisis

A

MAOIs

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9
Q

Patients wih parkinsons disease should take this drug with caution due to EPS

A

METOCLOPRAMIDE

CINNARIZINE

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10
Q

2 preop prophylaxis for CV surgery

A

Cefazolin

Cefuroxime

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11
Q

Carbapenem CI to pt with seizure

A

Imipenem

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12
Q

Prophylaxis for Gastroduodenal area, small intestine, non-obstructed

A

Cefazolin

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13
Q

Anesthetic used in caution in patirnts wih liver cirrhosis

A

Halothane

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14
Q

Prophylaxis for Biliary tract: open procedure, laparoscopic high risk

A
Cefazolin
Cefoxitin
Ampicillin sulbactam
Ceftriaxone
Cefotetan
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15
Q

Prophylaxis for Biliay tract:laparoscopic low risk

A

None

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16
Q

Prophylaxis for Uncomplicated Appendicitis

A

Cedfazolin + Metronidazole
Cefoxitin
Cefotetan

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17
Q

Drugs that causes malignant hyperthermia

A

Halothane

Succinylcholine

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18
Q

Prophylaxis for Colorectal surgery

Obstructed small intestine

A
Cefazolin/Ceftriaxone + Metronidazole
Ertapenem
Cefoxitin
Ampicillin sulbactam
Neomycin (Nichol's preparation)
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19
Q

Prophylaxis for neurosugical procedures

A

Cefazolin

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20
Q

Prophylaxis for breast and hernia

A

Cefazolin

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21
Q

Prophylaxis for Orthopedic Surgery

A

Cefazolin/ Ceftriaxone

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22
Q

Most cardiotoxic anesthetic

A

Bupivacaine

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23
Q

Elective colorectal sugery

A

OMBP

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24
Q

Nichols Condon Preparation

A

Consists of Neomycin and erythromycin given a day prior to colorectal surgery

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25
Q

What has been substituted for erythromycin bec of its effectiveness against anaerobic organisms in the gut?

A

Metronidazole

26
Q

Given prior to thyroid surgery to decrease vascularity and size of thyroid gland

A

Lugol’s iodine/ SSKI

27
Q

Given orior to thyroid surgey to control adrenergic symptoms

A

Propanolol

28
Q

Causes fetal hydantoin syndrome

A

Phenytoin

29
Q

Causes ftal renal agenesis

A

ACE inhibitors

30
Q

Cough in ACE-I is due to what substance?

A

Bradykinin

31
Q

Medical prophylaxis

Gonorrhea

A

Ceftriaxone

32
Q

Medical prophylaxis

Meningococcal infection

A

Rifampin
Minocycline
Ciprofloxacin

33
Q

Medical prophylaxis

Pneumocystis carinii

A

TMP SMX

Aerosolized pentamidine

34
Q

Medical prophylaxis

Syphilis

A

Benzathine penicillin G

35
Q

Medical prophylaxis

TB

A

Isoniazid

36
Q

Medical prophylaxis

Infective endocarditis in patients undergoing Dental procedures

A

Amoxicillin

37
Q

Medical prophylaxis

Leptospirosis

A

Doxycycline

38
Q

Medical prophylaxis

DVT

A

LMW heparin (Enoxaparin)

39
Q

Antiplatelet of choice for secondary stroke prevention

A

Aspirin (inhibits COX, TxA2)

40
Q

Migraine prophylaxis

A

Flunarizine
Propanolol
Lamotrigine (Steven-Johnsons’s syndrome)

41
Q
GI upset
Skin rashes
Headaxhe
Dizziness
Closure of epiphyseal plates in children
A

Fluoroquinolones

42
Q

Rash

Pseudomembranous colitis

A

Ampicillin

43
Q

Teratogenic
Carcinogenic
Headaches
Confusion

A

Griseofulvin

44
Q

Foscarnt toxicity

A

Nephrotoxicity

45
Q

Ganciclovir toxicity

A

Nephrotoxicity
Leukopenia/Neutropenia
Thrombocytopenia

46
Q

Toxic effects of TMP

A

Granulocytopenia
Leukopenia
Megaloblastic anemia

47
Q

Toxic effects of Azoles (keto and fluconazole)

A

Gynecomastia

Liver dysfunction

48
Q

Toxic effects of acyclovir

A

Nephrotoxicity
Delirium
Tremors

49
Q

Digitalis toxicity is increased by

A

Hypokalemia
Hypomagnesemia
Hypercalcemia

50
Q

Yellow perception
Gynecomastia
Hallucinations
Non specific symptoms

A

Digitalis toxicity

51
Q

Anti arrhythmics that causes torsades de pointes

A

Sotalol

Bepridil

52
Q

Drugs causing pulmonary fibrosis

A

Bleomycin
Amniodarone
Busulfa

53
Q

Prophylaxis for head and neck surgery: clean contaminated

A

Cefazolin/Cefuroxime + Metronidazole

Ampicillin Sulbactam

54
Q

DOC for chloroquine sensitive P. Falciparum

A

Chloroquine

55
Q

DOC for Chloroquine-resistant Malaria

A

Quinine

56
Q

MOA for Quinine

A

Forms complexes with plasmodium DNA and prevents strand separation

57
Q

Used in prophylaxis and treatment of chloroquine resistant p. Falciparum

A

Mefloquine

58
Q

Used in prophylaxis and treatment of chloroquine resistant p. Falciparum

A

Mefloquine

59
Q

DOC for Tpxoplamosis

A

Pyrimethamine-Sulfadoxine (Fansidar)

60
Q

Used in relapsing malaria, eradicates liver stages of P. Vivax and P. Ovale

A

Primaquine