Pharmacology & the Responsibilities of the PMHN Flashcards
(37 cards)
4 Phases of Drug Treatment
- Initiation phase
- Stabilization phase
- Maintenance phase
- Discontinuation phase
Key Nursing Responsibilities in the 4 Phases of Drug Treatment (3)
- Do a baseline assessment prior to initiating medication
- Proactively monitor and treat side-effects
- Education of patients and families
Major classes of psychiatric medications
- Antipsychotics
- Mood stabilizers
- Antidepressants
- Antianxiety
- Stimulants
Antipsychotics
- First Gen (typical)
Early 50s, discovered for psychosis or schizophrenia, chlorpromazine - Second Gen (atypical)
- Third Gen (atypical)
Mood Stabilizers
- Antimania
- Anticonvulsants
Antidepressants
- TCAs
- SSRIs
- SNRIs + NSSRIs
- MAOIs
Antianxiety
- Benzodiazepines
- Non-benzos
Stimulants
- Methylphenidate (Ritalin)
- Modifinil (provigil)
Knowledge Base Before Administration of Medication
- Classification of the medication you are giving
- Common & serious side effects
- Nursing responsibility specific to medication
Antipsychotic Medication Side Effects (Common) 6
Cardiovascular
Anticholinergic
Weight gain
Endocrine and sexual side effects
Blood disorders
Miscellaneous
Antipsychotic serious side effects
Neuroleptic Malignant Syndrome (NMS)
- a syndrome caused by neuroleptic medications that are dopamine receptor blockers. The classic signs are:
- hyperthermia
- lead-pipe rigidity
- changes in mental status
- autonomic nervous system changes
Acute Medication-related movement disorders: EPS
Extrapyramidal symptoms: involuntary movements that you cannot control
Acute Medication-related movement disorders: Dystonia
Involuntary muscle spasms, abnormal postures, oculogyric crisis, toricollis
Acute Medication-related movement disorders: Parkinsonism
Rigidity, akinesia (slow movement), tremor, mask-like face, loss of spontaneous movements
Acute Medication-related movement disorders: Akineisa
loss or impairment of voluntary muscle movement
Acute Medication-related movement disorders: Akathisia
inability to sit still, restlessness
Chronic medication-related movement disorders: Tardive Dyskinesia
- Irregular, repetitive involuntary movements of the mouth, face, and tongue, including chewing, tongue protrusion, lip smacking, puckering of the lips, and rapid eye blinking. Abnormal finger movements are common.
Antimania Medications
Lithium Carbonate
Antimania Anticonvulsants
Valproate
Carbamazepine
Gabapentin
Lamotrigine
Topiramate
Lithium Carbonate Side Effects
thirst, metallic taste, urinary frequency, fine tremor, drowsiness, and mild diarrhea
Lithium Carbonate Target Blood levels: Acute phase, and maintenance phase
Acute Phase: 0.8-1.4 mEq/L
Maintenance phase: 0.4-1 mEq/L
Lithium toxicity (MSVDL)
Severe diarrhea, vomiting, drowsiness, muscular weakness and lack of coordination
Anticonvulsant Side Effects: Carbamazepine
- dizziness, drowsiness, tremor, visual disturbances, nausea, and vomiting
- minimized by treating in low doses
- given with food
- weight gain
- Alopecia
- Thyroid function may be altered usually after 6 to 18 months. observe for dry skin, constipation, bradycardia, hair loss, and cold intolerance
Selective Serotonin Reuptake Inhibitors (SSRIs)
- Fluoxetine (Prozac)
- sertraline (Zoloft)
- Paroxetine (Paxil)
- Fluvoxamine (Luvox)
- Citalopram (celexa)
- Escitalopram (Lexapro)