Pharmodynamics

Question 1

What is the difference between pharmokinetics and pharmodynamics

Answer 1

pharmokinetics is what the body does to the drug, while pharmodynamics is what the drug does to the body

Question 1

True/False: the only effects classified as pharmacological are the therapeutic effects

Answer 1

false, all effects including undesirable are pharmacological effects

Question 2

Every drug has 3 different names, what are they?

Answer 2

Chemical name
Generic or nonproprietary name
Trade/Brand name

Question 3

What 4 things need to happen for a drug to produce its intended effect?

Answer 3

1.Have the right formulation/administration
2. reach the site of action
3. produce pharmacological effect
4. produced desired therapeutic effect

Question 4

Briefly describe receptor theory

Answer 4

Drug + receptor = drug/receptor complex
DR –> stimulus –> response (pharmacological effect

Question 5

What are the two implications of receptor theory

Answer 5

1. drugs modulate ongoing functions
2. drugs do not impart a new function

Question 6

What is the difference between agonist and antagonist?

Answer 6

Agonists: mimic endogenous substance
Antagonists: inhibit the effect of agonists or endogenous substances, they do not have intrinsic activity

Question 7

True/False: a drug has to act on a receptor

Answer 7

false, non receptor mediated drugs (ie chelating agents, structural analogues, osmotic agents)

Question 8

What are the three types of drugs that are non receptor mediated

Answer 8

1. chelating agents
2. structural analogs
3. osmotic agents