physiology Flashcards
(100 cards)
What is a bipotential tissue
Tissue that hasnt differentiate
What protein direct development as a male
SRY
With sry protein, gonadal medulla develops into…
Testis
In absence of SRY protein, gonadal cortex becoes…
Ovarian tissue
View sexual differentiation table
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2 type of cells in testis
Leydig cells
Sertoli cells
In women , Mullerian duct develops into … and wolffian duct …
Vagina
Uterus
Fallopian tubes
…degenerate
What is the pathway for male genitalia development
Presence of SRY gene => produces the SRY proteins
production of proteins SRY => gonad medulla differentiate into testis
testis has leydig cells and Sertoli cells
Leydig cells secrete testosterone => causes development of wolffian duct into vas deferens, epididymis and seminal vesicles
DHT control development of external genitalia
Sertoli cells secrete antimullarian hormone which causes regression of mullerian duct
Pathway for female genitalia development
No SRY gene so no proteins
Gonadal cortex diff differentiate into ovarian tissue
Gonadal medulla degenerate
Mullerian duct become vagina uterus fallopian tubes
wolffian duct degenerates
What are the sex steroid hormones Produced by the ovary
Estrogen
progesterone
What are the sex steroids produced by the testis
dihydrotestosterone
Testosterone
Do adrenal glands produce small amounts of sex steroids
Yes they do
What is the precursor of all sex steroids
Cholesterol
What’s enzyme convert testosterone to estradiol
Aromatase
What enzyme converts testosterone to dihydrotestosterone
5 reductase
In reproduction what hormone is produced by the hypothalamus
Gonadotropin releasing hormone GnRH
In reproduction what hormones are produced by the anterior pituitary
luteinizing hormone LH
follicle-stimulating hormone FSH
Pathway of hormonal control of reproduction
Stimuli comes to central nervous system
hypothalamus releases gonadotropin releasing hormone
gonadotropin releasing hormone causes release of Luiteinizing Hormone and follicle stimulating hormone from the anterior pituitary
Luiteinizing Hormone causes release of steroids and peptides from endocrine cells in the gonads
follicle-stimulating hormone Induce gamete production from the gonads
What is the effect if you have low androgen or estrogen
Absence or negative feedback with increased gonadotrophin level
Moderates estrogen or androgen effects
negative feedback with decreased gonadotropin level
High androgen level effect feedback
Negative feedback with decreased gonadotropin level
Sustain high estrogen affect on feedback
Positive feedback with increased Gonadotropin level
What are the external genitalia of males
Scrotum
penis
What is the common passageway in male genitalia
Urethra