physiology Flashcards

1
Q

what is the cell membrane primarily composed of

A

phospholipids

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2
Q

phospholipid head and tail

A

head - hydrophobic

tail hydrophilic

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3
Q

what does cholesterol do to the membrane

A

stiffens/hardens it

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4
Q

what substances can cross the phospholipid bilayer easily

A

uncharged polar molecules e.g. O2, CO2, water and NH3

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5
Q

what is response for the fluidity of the membrane

A

lipid bilayer

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6
Q

name a ligand binding receptor

A

hormone receptor

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7
Q

what are adhesion molecules important in

A

regulating cell shape, growth and differentiation - allowing cell to adapt to its immediate surrounding

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8
Q

what is a glycocalyx

A

carbohydrate and lipid layer that surrounds some cells

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9
Q

what serves as self identity markers in cells

A

membrane carbohydrates

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10
Q

what are aquaporins

A

water channels

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11
Q

define tonicity

A

the effect a solution has on cell volume

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12
Q

what effect does overheating have

A

protein denaturation, nerve malfunction, convulsion

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13
Q

what effect does dec body temp have

A

slow down cellular reactions and metabolism

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14
Q

normal ear drum temp range

A

35.5 - 37.5

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15
Q

normal rectal temp range

A

36.7-37.5

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16
Q

when will you have your lowest body temperature

A

morning

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17
Q

what effect does menstruating have on your temp

A

higher during the 2nd half cycle

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18
Q

BMR

A

minimum amount of energy needed to sustain vital body functions

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19
Q

what effect do adrenaline and thyroxine etc have on BMR

A

inc it

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20
Q

what fat do children and hibernating animals have high level of

A

brown

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21
Q

what does brown adipose tissue contain

22
Q

what does brown adipose tissue do

A

generate heat by short circuiting the mitochondrial battery - non shivering thermogenesis

23
Q

which part of the hypothalamic centre is activated by cold

24
Q

which part of the hypothalamic centre is activated by warmth

25
what is a pyrogen
a substance that produces fever
26
define fever
temp > 38 C
27
define hyperthermia
temp >40
28
define hypothermia
temp <35
29
what does heat exposure do to muscle tone
decrease it
30
what is the resting membrane potential of a typical nerve cell
-70mV
31
what equation can be used to calculate the equilibrium potential
Nernst
32
what equation can be used to calculate the membrane potential
goldman hodgkin katz
33
which type of diabetes is ketosis common in
type 1
34
what hormones are released from the adrenal gland is response to stress
adrenaline and cortisol
35
define MAP
the average arterial blood pressure during a single cardiac cycle
36
length of diastolic portion in comparison to systolic
diastolic is twice as long
37
normal MAP range
70-105mmHg
38
lower MABP needs to perfuse organs
60mmHg
39
where are the baroreceptors locate
aortic arch and carotid sinus
40
what are baroreceptors responsive to
stretch
41
what happens when baroreceptors are stimulated
parasympathetic stimulation the heart
42
MABP equation
MABP = CO x TPR
43
CO =
HR x SV
44
define SV
vol of blood pumped by each ventricle of the heart per heart beat
45
define TPR
sum of resistance of all peripheral vasculature in the systemic circulation
46
define AUTORHYTHMICITY
heart able to beat in the absence of external stimuli
47
how is intrinsic control of SV controlled
frank starling mechanisms
48
what are the main resistance vessels
arterioles
49
what is vasomotor tone
vascular smooth muscles partially constricted at rest
50
what is the vasomotor tone caused by
tonic discharge of sympa nerves resulting in continuous release of noradrenaline
51
what are the only smooth muscles that have parasympathetic innervation
penis and clitoris
52
what type of changes do baroreceptors only respond to and why
acute changes in BP | they reset and will only fire again if there is a new acute change in MAP above the new steady state level