Physiology Flashcards

1
Q

upper GI function

A

intake source and receptacle

initial digestion occurs

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2
Q

middle GI function

A

site where most of digestion and absorption occurs

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3
Q

lower GI tract function

A

storage channel for elimination of waste

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4
Q

4 layers of of GI wall +fxn

A

inner mucosal

submucosal (support)

muscularis (peristalsis, circular layer, longitudinal layer)

outer serosa

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5
Q

types of muscle contractions

A
mass movements 
tonic contractile 
phasic contractile 
segementing
haustral
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6
Q

peristalsis contractile activity

A

serves to propel forward food

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7
Q

mass movements

A

propulsive movement of unit within large intestine

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8
Q

tonic contractile activity

A

found between two organs, stable contraction

occludes lumen

typically in LES, UES, other sphincter

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9
Q

phasic contractile activity

A

periodic contraction

lasts few seconds and followed by relaxation

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10
Q

segmenting contractions

A

mix chyme with secretions and bring contents into contact with mucosa for digestion and absorption

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11
Q

haustral contractions

A

segmenting contraction with longer duration

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12
Q

components of enteric nervous system

A

myenteric plexus

submucosal plexus

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13
Q

myenteric plexus

A

aka Auerbach

between circular and longitudinal calls

concerned with motility

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14
Q

submucosal plexus

A

AKA Meissner

controlling function of ea. segment of intestinal tract

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15
Q

SNS effect on GI tract

A

via thoracocolumbar spinal cord

stimulation cause decrease in activity + decreased motility and secretions

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16
Q

PNS effect on GI tract

A

via vagus nerve

cause increase in activity including increased motility and secretions

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17
Q

areas of striated muscle in GI

A

pharynx, upper third of esophagus, external anal sphincter

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18
Q

increased smooth muscle ocontraciotn when

A

PNS stimulation

stretching smooth muscle (gas or constipation)

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19
Q

decreased excitability of smooth muscle contraction

A

SNS stimulation

20
Q

achalasia and neuromuscular

A

LES does not rely

21
Q

Hirschsprung dz and neuromuscular

A

lack of inhibitory enteric n. in colon

22
Q

ileus and neuromuscular

A

caused by trauma or infection + disruption of normal neuro hormonal regulation

23
Q

IBS and neuromuscular

A

altered sensory nerve fxn or altered motility

24
Q

involuntary motor impulses for oral and pharyngeal phases carried in: 4

A
  1. trigeminal (V)
  2. Glossopharyngeal (IX)
  3. Vagus (X)
  4. hypoglossal (XII)
25
impulses for esophageal phase are carried in
vagus (X)
26
rectosphinteric reflex
responsible for defecation contents cause relaxation of internal anal sphincter and urge to defecate occurs
27
functions of saliva
1. protection and lubrication 2. protective antimicrobial action 3. initiate digestion of starches
28
salvia produced and secreted by
parotid, submaxillary, sublingual and buccal glands
29
gastric secretion (cells) (4)
mucous secreting cells parietal cells cheif cells G sells
30
mucous secreting cells
barrier of protection
31
parietal cells
HCl and IF (b12)
32
chief cells
pepsinogen (converted to Pepsi when exposed to low pH)
33
G cells
secrete gastrin stimulates gastric acid and pepsinogen, increased gastric blood flow, stimulate scontraction, growth of gastric and intestinal mucosal cells
34
functions fo secretory glands
mucous production (lubricate, protect) secrete fluids and enzymes (digestion of nutrients)
35
GI hormones
cholecystokinin gastrin secretin
36
cholecystokinin
stim cox of GB | secretion of enzymes, slows gastric emptying, decreases food intake
37
gastrin
stimulates secretion of gastric acid and pepsinogen increases gastric blood flow, simulates gastric smooth muscle and stimulates growth of gastric and intestinal cells
38
secretin
stimulates secretion of bicarbonate contains fluids by pancreatic and liver
39
secretions of small intstine
bruners glands (alkaline mucous) secretion 2 secretion 3 (enzymes peptidases and disaccharidases)
40
functions of gut flora
metabolic activity (fermentation of indigestible) trophic effects /grooming protection colonization
41
when does colonization take place?
begins shortly after birth influenced by passage thru birth canal and others
42
digestion
dismantling food into constituent parts
43
processes of digestion
hydrolysis enzyme cleavage fat emulsification
44
absorption
process of moving food into the internal environment active transport and diffusion
45
fxn of intestinal brush border
aid in digestion of carbs and proteins | adhere to border of villous structure