Malignancy App Flashcards Preview

GI 1 > Malignancy App > Flashcards

Flashcards in Malignancy App Deck (13)
Loading flashcards...
1
Q

2 different types of esophageal Carcinoma + site

A

SCC - proximal and middle

Adenocarcinoma - distal

2
Q

why does SCC spread rapidly?

A

esophagus lymph nodes are located in the lamina propria + esophagus lacks serosa so it can directly spread and quickly get into the lymph nodes

3
Q

CA risk factor for

Hammartomatous polyp

A

intermediate risk

4
Q

CA risk factor for

Hyperplastic polyp

A

low - no risk

5
Q

CA risk factor for adenomatous polyps

A

High risk

6
Q

polyp with gravest risk of CA

A

Tubulovillous is the gravest risk

7
Q

types of adenomatous polyps

A

Tubular, villous, tubulovillous

high risk

8
Q

local SCC esophageal cancer spread

gravest risk

A

erosion into the aorta causing massive upper GI hemorrhage

9
Q

Esophageal CA belt

location + type

A

Caspian sea through china,

elevated risk of cancer of the esophagus

SCC - 90%

10
Q

why do we think esophageal CA belt is predisposed?

A

poor nutritional status
low fruit/veggies diet
beverages high in temp
smoking

11
Q

SCC risk factors

A
  1. tobacco
  2. alcohol
  3. low fruits and veggies
  4. Nitroasamine compounds
  5. achalasia
12
Q

nitrosamine compounds

A

risk factor for BOTH esophageal and gastric CA

cured meats (bacon)
Japanese fish
pickled food
beer

13
Q

why is achalasia a risk factor for esophageal CA

A

increased contact time of harmful food due to constriction