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Flashcards in physiology Deck (28)
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1

how much does haemoglobin increase the carrying capacity of RBC

in red blood cells increases O2 carrying capacity to 200ml/L

2

how many ml's of oxygen can dissolve in plasma

3ml

3

alveoli O2 partial pressure

100mmHg - oxygen tension

4

oxygen demand of resting tissues

250ml/min 25% of 02 extracted at rest

5

how many ml's of oxygen binds to one gram of haemoglobin

1.34ml

6

how long does oxygen saturation of haemoglobin take

Saturation is complete after 0.25s contact with alveoli (total contact time ~0.75s)

7

CO's affinity for haemoglobin is how many times greater than oxygens

250x

8

what are the 5 types of hypoxia?

hypoxaemic
anaemic
stagnant
histotoxic
metabolic

9

how is CO2 transported

7% in plasma
23% as deoxyhemoglobin to from cardamino compounds
70% form carbonic acid which dissaciates into bicarbonate and hydrogen ions

10

hypoventilation causes

respiratory acidosis

11

hyperventilation causes

alkalosis

12

pulmonary ventilation

total air movement into/out of lungs

13

Alveolar ventilation

fresh air getting to alveoli and therefore available for gas exchange (functionally much more significant!)

14

what is atmospheric pressure

760mmHg

15

Boyle’s Law

states that the pressure exerted by a gas is inversely proportional to to its volume (P a 1/V).

16

Dalton’s Law

states that the total pressure of a gas mixture is the sum of the pressures of the individual gases.

17

Charles Law

states that the volume occupied by a gas is directly related to the absolute temperature (v a T)

18

Henry’s Law

states that the amount of gas dissolved in a liquid is determined by the pressure of the gas and it’s solubility in the liquid

19

intrapleural pressure is

-3 mm Hg subatmospheric

20

transpulmonary pressure is

always positive

21

average volumes exchanged in a minute

250ml oxygen
200ml carbon dioxide

22

DRG is responsible for

setting the automatic rhythm of breathing

23

acidosis stimulates

ventilation to be increases

24

alkalosis stimulates

ventilation inhibition

25

pulmonary circulation is

high flow, low pressure system system ~25mmHg

26

tissue oxygen values

40 mmHg (5.3kPa)

27

tissue carbon dioxide values

46 mm Hg 6.3kPA

28

distribution of blood flow in the lungs is determined by

hydrostatic blood pressure and alveolar pressure