Flashcards in Physiology of the Pituitary Gland Deck (11):
Which hormones are secreted by the anterior pituitary?
What hormones are stored in the posterior pituitary?
Which hormones are involved in baseline pituitary tests?
Briefly what are dynamic tests?
Stimulate or suppress the hormone that you want to know something about. These are done after baseline pituitary tests
What is the short synacthen test and what results would you expect to be normal and abnormal?
Patient given synthetic ACTH and blood cortisol measured at 0, 30 and 60mins.
30min cortisol >600nmol/L = normal
30mincortisol <400nmol/L = abnormal
What does an abnormal synacthen test suggest and , what should then be done?
Suggests adrenal insufficiency
Measure ACTH - low = pituitary disease
High = adrenal disease
Describe the water deprivation test.
Patient is given nothing to drink all day to see if they can concentrate their urine (should be twice serum concentration). If this is not possible then diabetes insipidus can be diagnosed
What is the insulin stress test and what is it used for?
Try to get blood sugar really low by giving insulin. This stresses pituitary out to produce more hormones.
Best test for steroid response.
What are normal results from the insulin stress test?
Cortisol and GH response every 30 min for 2-3 hrs
Normal cortisol >500
Normal GH >7ug/l
What is prolactin controlled by?
Negative dopamine control