Reproductive Endocrinology Flashcards Preview

Endocrine > Reproductive Endocrinology > Flashcards

Flashcards in Reproductive Endocrinology Deck (26):
1

Name the earliest recognisable germ cell.

Primordial germ cell

2

2 polar bodies in the germ cell signifies what?

sperm entry and the completion of the 2nd meiotic division

3

In what phase of the ovarian cycle are oestrogen and progesterone secreted in? What is the signficance of their secretion?

Oestrogen - Follicular phase
Progesterone - Luteal phase
essential for preparation of uterine lining for implantation

4

Degeneration of corpus luteum signals what? What does it degenerate to?

Start of a new follicular phase - fertilisation did not occur
Degenerates to the corpus albicans

5

If fertilisation has occured what does the corpus leuteum do?

Corpus luteum persists and produces increasing quantities of progesterone and oestrogen until after pregnancy

6

What does the hypothalamus secrete that acts on the anterior pituitary to produce hormones?

GnRh
Gonadotrophin releasing hormone

7

What does the anterior pituitary release?

FSH
LH
GH
ACTH
TSH

8

What does the posterior lobe of the pituitary gland secrete?

ADH
Oxytocin

9

What separates the hypothalamus in two?

The 3rd ventricle

10

When GnRH acts on the anterior pituitary which hormones are released?

FSH - follicle stimulating hormone
LH - lutenizing hormone

11

What is the function of FSH?

Acts on ovary
Stimulates development of follicles

12

What is the function of LH?

Acts on ovary
Stimulates follicle maturation, ovulation and development of the corpus luteum

13

FSH and LH stimulate the secretion of what and stimulate what?

Oestradiol and stimulate ovulation

14

What is the function of the theca cells?

Produce androgen which is converted by the granulosa (aromatase) to oestradiol

15

What is the function of oestradiol?

Thickens endometrium
Thins cervical mucus

16

Oestrogen does what to the FSH production by the anterior pituitary? What does this do?

Suppresses it
Allows the selection of dominant follicle

17

The high levels of oestrogen at mid cycle cause what?

Cause the hypothalamus to release GnRH
Causes a surge in release of FSH and LH from the anterior pituitary

18

After ovulation what happens to the levels of LH and FSH?

Decrease

19

If fertilisation occurs, what does the developing embryo produce? What are their functions?

hCG (chorionic gonadotrphin) - Functions to maintain the corpus luteum
Progesterone - functions to support pregnancy and suppress ovulation

20

When does the placenta take over the role of producing progesterone and what happens to the corpus luteum?

6 weeks
Corpus luteum degenerate to the corpus albicans

21

Which hormones stimulate spermatogenesis?

FSH and testosteroe

22

Which hormone stimulates testosterone secretion?

LH

23

What decreses secretion of FSH?

Inhibin

24

Testosterone does what to the releasing of GnRH and LH?

Decreases it - negative feedback

25

Where is inhibin and androgen binding globulin (ABG) produced?

Sertoli cell in seminiferous tubule

26

Which part of the embryo impants on the wall of the uterus?

Blastocyst