Physiology Review III Flashcards Preview

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Flashcards in Physiology Review III Deck (55):
1

morning sickness

hCG

2

gestational hyperthyroidism

hCG binds TSH receptors

3

other hCG effects

leydig - testosterone
fetal adrenal cortex

4

progesterone synthesis

CYP11A1, 3B HSD

5

progesterone

decreased uterine contractions
-increased secretions
-increased fat deposition

6

estrogen

necessary for parturition

7

E:P ration

decreased progesterone - allows PRL to act

8

hPL/hCS

lipolytic
increased glucose for fetus

9

placental limitations

no cholesterol
no enzymes for estrogen

10

PRL

estrogen stimulates release
lactotroph hypertrophy

11

sheehans syndrome

lactotroph hypertrophy

12

ADH changes

lower threshold
progesterone effect

13

thyroid changes

total raises
free same

bc of TGB

14

11-beta DH type 2

inactivates cortisol

15

increased aldosterone?

estrogen
-increased angiotensinogen and renin

but progesterone blunts action

16

increased plasma volume

incrased NaCl retention - aldosterone
increased water retention - ADH

17

stroke volume

decreased
IVC compression
decreased VR, EDV, SV

18

CO distribution

uterus, renal, skin, heart, breasts

same - brain, gut, skeleton

19

TPR

decreased
low R circuit
vasodilation
low viscosity

20

edema

increased V pressure in legs
decreased capillary osmotic P (less proteins)

21

alveolar ventilation

increased

22

PCO2

decreased
respiratory alkalosis

23

respiratory alkalosis

renal compensation
-increased bicarb secretion

24

fetal Hg

higher affinity
left shift

25

CO

increased HR and SV

26

renal

increased RBF and GFR
Na retention, water retention

decreased serum Na

27

GI

reflux
progesterone - decreased emptying, LES tone

increased abdomen P
decreased mobility

28

mom nutrition

needs protein, iron, folate

29

quiescent uterus

relaxin and progesterone

30

braxton hicks

weak contractions
false labor

31

stages of parturition

1 contractions - dilation < 10cm
2 > 10cm to delivery
3 delivery of placenta

32

prostaglandins

stimulated by estrogen, oxytocin, stretch

initiate labor**
soft cervix

can be used to induce labor

33

aspirin

inhibits prostaglandins

34

ferguson reflex

oxytocin - increased contractions - increased positive feedback for oxytocin

35

estrogen effects end of term

more gap junctions
more oxytocin receptors
more prostaglandin synthesis

36

CRH

from placenta
-increase sensitivity to prostaglandins and oxytocin in uterus

37

relaxin

from CL and placenta
soften ligaments

38

cortisol increase

surfactant in fetal lungs

39

nipple

stratified squamuos dry
melanocytes
elastic fivers
meissners and pacinian corpuscles

40

functional unit

lobule

41

myoepithelium

around alveoli
no nerves
only oxytocin

42

intralobular CT

loose

43

interlobular CT

dense

44

mammogenesis

estrogen

45

estrogen breasts

ducts

46

progesterone breasts

alveoli

47

breast cancer

lots have estrogen receptor

different Tx pre and post menopause

48

colostrum

IgG, nutrients, fat

49

sucking

1 - decreased dopamine, increased PRL
2 - increased oxytocin
3 - decreaed GnRH - inhibit ovarian cycle

50

cow fat

high protein - casein

51

breast milk immunity

IgA
WBC, M0s
growth factors

52

mammogenic

E/P

53

lactogenic

estrogen, hCS, decreased progesterone

54

galactokinetic

oxytocin

55

galactopoietic

PRL