Physiology Review I Flashcards Preview

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Flashcards in Physiology Review I Deck (53)
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1

leydig cells

produce testosterone

2

stimulation of leydig cells

hCG - from placenta
fetal LH
LH

3

sertoli cells

AMH

4

DHT effects

2 sex characteristics
male external
prostate

5

5 alpha reductase

testosterone > DHT

6

oligospermic men

hCG therapy

7

androgen insensitivity

x-linked recessive
no androgen receptor

8

puberty

pulsatile GnRH

9

aromatase

can get testosterone - estradiol

breasts in genetic male

10

Tanner stages

1 - preadolescent
2 - enlarged testes
3 - enlarged penis
4 - dark scrotum / penile growth
5 - adult sized

11

ABP

keeps high T in testes

12

hypogonadism

low spermatogenesis or steroidogenesis

low FSH, LH, and T

13

prostate cancer

GnRH therapy
continuous high dose
suppress gonadotropin release

14

sertoli cell function

blood-testis barrier
produce ABP
AMH, aromatase, inhibin production

15

testosterone therapy

won't help infertility
bc of the need for high intratesticular T levels

this will only inhibit LH secretion
-leads to decreased testosterone

16

eunuchoidism

lack secondary sex characteristics

17

lobule of testes

split by CT septae

18

leydig cell shape

large polyhedral
rounded nuclei w/ 1-2 nucleoli
produce androgens

close to vascular channels

19

3 phases spermatogenesis

spermatocytogenesis
meiosis
spermiogenesis

20

spermatocytogenesis

PGC > spermatogonia > primary spermatocyte

21

meiosis

primary spermatocyte >
secondary spermatocyte >
spermatid

22

spermiogenesis

spermatid > spermatozoa

23

type B spermatogona

46/2N
to 2x primary spermatocyte

24

primary spermatocyte

largest**

25

peritubular contractile cells

in seminiferous tubules

26

seminiferous tubules

solid - preadolescent
canalize - adult

27

spermatogenic epithelium

4-8 layers stratified germ cells
supporting sertoli cells scattered

28

sertoli cell histo

tall columnar
large pale oval nuclei
prominent nucleus
membrane infoldings
cytoplasm indented

29

blood testis barrier

sertoli cells
tight junctions
-spermatocytes from spermatogonia

30

spermatogonia

sit on BM

46 2N