Flashcards in Pituitary Disorders Deck (24):
the pituitary gland consists of 2 parts, the anterior and posterior. what are other names related to these parts?
anterior = adenohypophysis
posterior = neurohypophysis
the anterior secretes which six hormones
TSH, ACTH, GH, prolaction, LH, FSH
what 2 hormones are released by the posterior?
ADH and oxytocin -- they are stored in the hypothalamus and then released by posterior pituitary
______ and _________ activate release of substances by posterior pituitary gland when they are stimulated by nerve impulses from the hypothalamus
ACh and NE
what is hyperpituitarism?
oversecretion of one or more of the hormones secreted y the pituitary
what is oversecretion of GH?
acromegaly or gigantism
what is oversecretion by the pituitary gland caused by?
hormone secreting pituitary tumor, Cushing's Disease (over secretion of ACTH), amenorrhea and hyperthyroidism
Tumors of the pituitary have 3 systemic effects:
1. excessive or abnormal growth patterns
2. hyperprolactinemia (amenorrhea, galactorrhea, gynecomastia)
3. overstimulation of one or more of the target glands resulting in release of excessive ATCH, TSH, or FSH/LH
s/s of low TSH = hypothyroid
weakness, muscle aches, stiffness
s/s of high TSH = hyperthyroid
nervousness, fatigue, weakness, tachycardia, trmeor
s/s of acromegaly/gigantism
enlargement of hands, feet, face, jaw
parasthesia of hands
sweating, HA, impotence
joint pain, muscle weakness, and reduce exercise tolerance
what is the medical manage of hyperpituitarism - acromegaly?
resection of tumor, suppression of GH with somatostatin, and external radiation
what are PT implications for acromegaly
progress cautiously; focus on: energy conservation, joint proteciton and fall preventio
what are the s/s of hypopituitarism - GH
regression of sexual characteristics (decreased LH/FSH)
what causes hypopituitarism - ACTH
adrenocortical insufficiency = diminished secretion of adrenocortical hormones by the adrenal cortex
what are s/s of hypopituitarism -LH and FSH
decreased production of sex hormones (estrogen, progesterone, and testosterone)
what is the name for hyperpituitarism - ACTH
what are the s/s of cushing's disease?
moon face, osteoporosis, buffalo hump, wasted limbs, abdominal obesity, cardiac hypertrophy and poor wound healing
what are the s/s of hypopituitarism - ACTH
glucocorticoid defieciency = hypoglycemia, nausea, abdominal pain, and orthostatic hypotension
what is the name for hyperpituitarism - ADH
SIADH = syndrome of inappropriate antidiuretic hormone
s/s of SIADH
excessive water retention and water intoxication; hyponatremia (sodium depletion)
what are s/s of hyponatremia?
HA, confusion, seziures, decreased consciousness, restlessness, muscle spasms, weakness, N/V
what is the name for hypopituitarism - ADH