pkpd module 4 Flashcards
1
Q
if limited solubility is saturated
A
dec F
2
Q
if active absorption is saturated
A
dec F
3
Q
if efflux transport is saturated
A
inc F
4
Q
if p-gp induction is saturated
A
dec F
5
Q
if tubular secretion is saturated
A
dec renal CL
6
Q
if active tubular reabsorption is saturated
A
inc renal CL
7
Q
if biliary secretion saturated
A
dec hepatic CL
8
Q
if capacity limited matabolism is saturated
A
dec CL
9
Q
if saturable first-pass metabolism saturated
A
inc F
10
Q
if autoinduction saturated
A
inc CL
11
Q
if mechanism-based autoinduction saturated
A
dec CL
12
Q
if saturable plasma protein binding saturated
A
inc V, change CL depends on E
13
Q
if saturable tissue binding saturated
A
dec V
14
Q
if half life changes, think change in
A
CL
15
Q
if V or Cmax changes, think change in
A
F
