Placentation Flashcards

1
Q

what is gastrulation?

A

the process of a blastocyst turning into a 3-layered entity called a gastrula

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2
Q

what 3 layers are present in a gastrula?

A
  1. endoderm
  2. ectoderm
  3. mesoderm
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3
Q

what will the trophectoderm become after gastrulation?

A

the chorion of the placenta

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4
Q

what will the inner cell mass become after gastrulation?

A

the 3 germ layers of the gastrula

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5
Q

which of the 3 germ layers develops first after gastrulation?

A

endoderm

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6
Q

where does the endoderm develop?

A

around the inside of the blastocoele cavity

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7
Q

what forms after the endoderm develops around the inside of the blastocoele cavity?

A

the yolk sac

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8
Q

which germ layer develops after the endoderm and where?

A

the ectoderm, around the outside of the trophectoderm

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9
Q

where does the mesoderm develop?

A

between the yolk sac and trophectoderm

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10
Q

what 7 things will the ectoderm become in both males and females?

A
  1. CNS
  2. Sense organs
  3. mammary glands
  4. sweat glands
  5. skin
  6. hair
  7. hooves
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11
Q

what 2 things will the ectoderm become in females?

A
  1. posterior vagina

2. vulva

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12
Q

what 3 things will the ectoderm become in males?

A
  1. penis
  2. scrotum
  3. cowper’s gland
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13
Q

what 6 things will the mesoderm become in both males and females?

A
  1. circulatory system
  2. skeletal system
  3. muscular system
  4. reproductive tract parts
  5. kidneys
  6. urinary ducts
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14
Q

what will the mesoderm become in females?

A

everything internal to the anterior vagina

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15
Q

what will the mesoderm become in males?

A

prostate and everything before

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16
Q

what 7 things will the endoderm become in both males and females?

A
  1. digestive system
  2. liver
  3. lungs
  4. pancreas
  5. thyroid gland
  6. other glands: not all, but many of them
  7. primordial germ cells
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17
Q

list the 4 placental membranes

A
  1. yolk sac
  2. amnion
  3. allantois
  4. chorion
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18
Q

what is the role of the yolk sac in birds?

A

nourish the embryo

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19
Q

what is the role and fate of the yolk sac in mammals?

A

source of blood cells and PRIMORDIAL GERM CELLS, will atrophy

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20
Q

describe the amnion (3)

A

non-vascular, fluid-filled, smooth

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21
Q

what produces the fluid that fills the amnion?

A

the fetus

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22
Q

what is the role of the amnion?

A

protective cushion, for physical and mechanical protection (like a water balloon)

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23
Q

what happens to the amnion at birth?

A

it ruptures

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24
Q

is the amnion still full of fluid when it ruptures at birth?

A

no, it is almost out of fluid by parturition

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25
which placental membrane has vasculature?
the allantois
26
where does the vasculature of the allantois come from?
the fetus
27
what happens to the allantois and what is the result?
fuses with the chorion to form the chorioallantois (or allantochorion), brings blood vessels to chorion
28
what is the chorion? (2)
the outermost placental membrane, the attachment to the mother
29
what takes place at the chorion?
exchange between mother and fetus
30
list the 4 categories of placenta when classifying based on shape or distribution of chorionic villi
1. cotyledonary 2. diffuse 3. zonary 4. discoid
31
list the 3 animals with a cotyledonary placental attachment
1. cow 2. sheep 3. goat (ruminants)
32
list the 2 animals with a diffuse placental attachment
1. pig | 2. horse
33
describe a diffuse placental attachment
like velcro, evenly distributed
34
list the 2 animals with a zonary placental attachment
1. dog | 2. cat
35
describe a zonary placental atatchment
like a belt
36
what animal has a discoid placental attachment?
humans
37
describe a discoid placental attachment
like a plunger
38
what 2 types of cotyledonary attachments are there and which animal has which type?
1. convex: cotyledon wraps around, bovines have | 2. concave: cotyledon burrowed into middle, ovines have
39
what makes a placentome?
cotyledon + caruncle
40
what are BNGCs
binuclear giant cells
41
what do BNGCs do?
migrate from the chorion to the endometrial epithelium in ruminants; invade endometrium
42
what 2 hormones do BNGCs secrete?
1. placental lactogen | 2. pregnancy specific protein B
43
how much of the placenta to BNGCs make up in volume/weight?
about 20% of fetal placenta
44
what are placental lactogens (hormone type and prupose)
protein hormones that have prolactin-like activity to stimulate milk synthesis, and also growth-hormone like activity
45
what animals do NOT have placental lactogens?
pigs and mares
46
what is a possible second function of placental lactogens?
may regulate maternal metabolism to facilitate fetal growth
47
when are there higher levels of placental lactogen and what does this cause?
higher levels in the last 1/3 of gestation, facilitates higher milk production
48
why do dairy cows have higher blood concentrations of placental lactogens than beef cows?
they have been selected to produce more milk
49
what is the role of microcotyledons in a diffuse placents?
increase placental surface area
50
where do the endometrial cups in the mare develop from? (2)
both the trophoblast and the endometrium
51
when do endometrial cups form in mares?
35 d of gestation, AFTER maternal recognition
52
what do the endometrial cups in mares secrete?
eCG, also called PMSG
53
what do the endometrial cups in mares do?
allows the mare to go from one CL to several accessory CLs to increase P4
54
what happens to endometrial cups after 100-140 days?
they are sloughed off
55
what happens to the endometrial cups if a mare loses her pregnancy before days 100-140?
the cups will stay until that time
56
describe the vasculature of a zonary placenta
vasculature focused into chorionic band
57
describe the attachment of a discoid placent
attachment in a big thick disk
58
when classifying based on number of tissue layers, list the 3 types of placenta and the number of tissue layers each has
1. epitheliochorial type (6) 2. endothelialchorial type (4) 3. hemochorial type (3)
59
what animals have epitheliochorial type placentas?
most domestic species
60
list the 6 tissue layers from maternal side to fetal side in an epitheliochorial type placenta
1. endometrial capillary 2. endometrial interstition 3. endometrial epithelium 4. chorial epithelium 5. chorial interstition 6. chorial capillary
61
list the 4 tissue lasyers from maternal side to fetal side of endothelialchorial type
1. endometrial epithelium 2. chorial epithelium 3. chrorial interstition 4. chorial capillary
62
what maternal layers does the hemochorial type placenta have?
NONE HA BITCH
63
what 3 tissue layers does a hemochorial type placenta have?
fetl tissue layers only 1. chorial epithelium 2. chorial interstition 3. chorial capillary
64
does fetal and maternal blood mix during gestation?
NOOOOOOO NEVER
65
when might mixing of fetal and maternal blood occur and what might it result in?
may occur at parturition and may result in antibodies against specific fetal blood type
66
who is affected by the mixing of fetal and maternal blood at parturition?
future neonates or fetuses
67
what is erythoroblastosis fetalis? how treat?
occurs in humans, when antibodies cross the placents, give Rh factor to treat
68
what is neonatal isoerythrolysis?
occurs in cats and horses, carry antibodies in colostrum and are absorbed in the first 24 hours of neonate's life
69
what do you do with isoerythrolysis?
just don't let baby nurse colostrum from mom, once produce milk baby can nurse
70
why do you not have to treat isoerythrolysis to maintain pregnancy?
antibodies don't cross placenta in nonhumans, so only colostrum is affected
71
to what animals does implantation refer?
primates
72
to what animals does attachment refer?
nonprimates
73
list the 3 types of implantation/attachment
1. superficial/centric 2. eccentric 3. interstitial
74
describe superficial/centric attachment and in who it occurs?
chorion lies opposed to uterine wall; in farm animals
75
describe eccentric attachment and in who it occurs?
chorionic sack in a uterine fold, in rodents
76
describe interstitial implantation and in who it occurs?
embryo digests part of uterine wall, embryo burrows into uterus, in humans
77
list the 2 degrees of tissue loss at parturition, and which occurs in what type of attachment/implantation
1. deciduate: high degree of tissue loss, in eccentric and interstitial 2. indeciduate or nondeciduate: low to no degree of tissue loss, in superficial/centric
78
how long can primates bleed after parturition?
for 6-8 weeks