population genetics & natural selection Flashcards
(38 cards)
what evolves and what doesn’t?
population evolves but individuals don’t
what is a population?
localized group of individuals of the same species
what is a gene pool?
the total aggregate of genes (and their alleles) in the population at one time
Why might we need to estimate frequencies of genotypes in a population?
- To predict how many individuals will inherit a genetic disease
- To estimate the proportion of individuals who are ‘carriers’ of a genetic disease
How do we predict genotypes in a population?
Hardy-Weinberg equation
what is the allele frequency equation?
Allele frequency - p + q = 1
what is the allele frequency equation?
Allele frequency - p + q = 1
what is genotypic frequency equation?
Genotypic frequency - p2 + 2pq + q2 = 1
how can we predict genotypic frequency in a population?
through allele frequency
what are p and q in the Hardy-Weinberg equation?
p = frequency of dominant allele
q = frequency of recessive allele
what is pq in the Hardy-Weinberg equation?
heterozygous
what happens in an x-linked trait for females and males?
for an x-linked trait:
- females need to be homozygous recessive to get the disease
- males need just one recessive allele
what are ways allele frequency can change by?
- Non - random mating
- Random Genetic Drift
- Bottleneck Effect
- Founder Effect
- Natural Selection
- Gene Flow or Migration
- Mutation
what are two different types of nonrandom mating?
- assortative mating
- inbreeding
what is assortative mating?
attraction phenotype similar to your own
what is disassortative mating?
goes out of way to not get similar phenotype to your own
what is random genetic drift?
A random change in allele frequencies due to sampling
error over generations
what is inbreeding?
mating with someone who shares similar genes with you
how does genetic drift happen quickly?
genetic drift happens quickly over a small population
what is the bottleneck effect?
original population has equal frequencies but due to some event the population reduces leading to bottle neck effect hence one of the allele is completely gone and the other becomes rare
what is the founder’s effect?
what happens when you establish a new population
what happens when there is a few founding individuals?
can’t capture all of the diversity in the parent population
when is bottleneck effect pronounced?
tiny population
what happens for genetic diversity overtime in the founders effect?
- takes really long time to evolve
- old population has more genetic diversity than new