PPI Flashcards

(9 cards)

1
Q

Key issues of PPI

A

Increased risk of fractures
Increased risk of CDIFF
Mask gastric cancer

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2
Q

Electrolytes PPI disturb

A

Hypomagnesaemia
Hyponatraemia

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3
Q

MHRA PPI

A

Very infrequent cases of subacute cutaneous lupus erythematous have been reported. drug induced can occur weeks, months and even years after exposure

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4
Q

PPI counselling

A

Take 30-60 mins before food
Do not take any indigestion remedies 2 hours before or after

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5
Q

Omeprazole x MTX

A

Reduces clearance of MTX

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6
Q

Omeprazole x phenytoin

A

Enhance effects (monitor)

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7
Q

Omeprazole x warfarin

A

May increase INR (monitor if PPI is started/stopped)

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8
Q

What dose is PPI for h.pylori

A

BD

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9
Q

PPI cautions

A

Patients at risk of osteoporosis
Vitamin b12 deficiency

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